Golgi scaffold protein PAQR3 as a candidate suppressor of gastric cardia adenocarcinoma via regulating TGF‐β/Smad pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24617
Abstract: To investigate the function of PAQR3 in gastric cardia adenocarcinoma (GCA) and understand the possible mechanism of PAQR3 in regulating epithelial–mesenchymal transition (EMT). read more here.
Keywords: gastric cardia; golgi scaffold; cardia adenocarcinoma; scaffold protein ... See more keywords
NNMT enriches for AQP5+ cancer stem cells to drive malignant progression in early gastric cardia adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Gut"
DOI: 10.1136/gutjnl-2022-328408
Abstract: Objective Early gastric cardia adenocarcinoma (EGCA) is a highly heterogeneous cancer, and the understanding of its classification and malignant progression is limited. This study explored the cellular and molecular heterogeneity in EGCA using single-cell RNA… read more here.
Keywords: malignant progression; stem cells; progression; cardia adenocarcinoma ... See more keywords
The Hippo signaling effector WWTR1 is a metastatic biomarker of gastric cardia adenocarcinoma
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DOI: 10.1186/s12935-019-0796-z
Abstract: BackgroundGastric cardia adenocarcinoma (GCA) is an aggressive subtype of gastric cancer with a high metastatic rate. However, the metastatic biomarker of GCA has not been established.MethodsTo search for the biomarker for GCA metastasis, we here… read more here.
Keywords: metastatic biomarker; biomarker; wwtr1; cardia adenocarcinoma ... See more keywords
miR-1262 suppresses gastric cardia adenocarcinoma via targeting oncogene ULK1
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer"
DOI: 10.7150/jca.46971
Abstract: Gastric cardia adenocarcinoma (GCA) is one of two main gastric cancer subtypes and has its own epidemiological, pathogenic and clinical characteristics. Genetic polymorphisms locating in a microRNA (miRNA) gene enhancer could transcriptionally regulates miRNA expression… read more here.
Keywords: gastric cardia; oncogene ulk1; mir 1262; mir ... See more keywords