Investigating cardiac β-adrenergic nuclear signaling with FRET-based biosensors.
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DOI: 10.1016/j.ando.2020.04.001
Abstract: By activating membrane β-adrenergic receptors (β-AR), noradrenaline and adrenaline are the most powerful stimulators of cardiac function. β-ARs are coupled to the synthesis of cAMP, which activates the cAMP-dependent protein kinase (PKA). PKA regulates the… read more here.
Keywords: activation; cardiac adrenergic; nuclear signaling; adrenergic nuclear ... See more keywords