Global vs local control of cardiac alternans in a 1D numerical model of human ventricular tissue.
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DOI: 10.1063/5.0005432
Abstract: Cardiac alternans is a proarrhythmic state in which the action potential duration (APD) of cardiac myocytes alternate between long and short values and often occurs under conditions of rapid pacing of cardiac tissue. In the… read more here.
Keywords: constant pacing; tissue; model human; cardiac alternans ... See more keywords
Modulation of Cardiac Alternans by Altered Sarcoplasmic Reticulum Calcium Release: A Simulation Study
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DOI: 10.3389/fphys.2018.01306
Abstract: Background: Cardiac alternans is an important precursor to arrhythmia, facilitating formation of conduction block, and re-entry. Diseased hearts were observed to be particularly vulnerable to alternans, mainly in heart failure or after myocardial infarction. Alternans… read more here.
Keywords: calcium release; sarcoplasmic reticulum; calcium; cardiac alternans ... See more keywords