Optimizing a spontaneously contracting heart tissue patch with rat neonatal cardiac cells on fibrin gel
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1895
Abstract: Engineered cardiac tissues have been constructed with primary or stem cell‐derived cardiac cells on natural or synthetic scaffolds. They represent a tremendous potential for the treatment of injured areas through the addition of tensional support… read more here.
Keywords: cardiac cells; patch; density; tissue ... See more keywords
Rescuing Cardiac Cells and Improving Cardiac Function by Targeted Delivery of Oxygen-Releasing Nanoparticles after or Even before Acute Myocardial Infarction.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c10043
Abstract: Myocardial infarction (MI) causes massive cell death due to restricted blood flow and oxygen deficiency. Rapid and sustained oxygen delivery following MI rescues cardiac cells and restores cardiac function. However, current oxygen-generating materials cannot be… read more here.
Keywords: function; cardiac function; myocardial infarction; heart ... See more keywords
Essential role of the Na+-Ca2+ exchanger (NCX) in glutamate-enhanced cell survival in cardiac cells exposed to hypoxia/reoxygenation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13478-x
Abstract: Myocardial ischemia culminates in ATP production impairment, ionic derangement and cell death. The provision of metabolic substrates during reperfusion significantly increases heart tolerance to ischemia by improving mitochondrial performance. Under normoxia, glutamate contributes to myocardial… read more here.
Keywords: cardiac cells; cell; survival cardiac; role ... See more keywords
Unexpected effect of urate on hydrogen peroxide-induced oxidative damage in embryonic chicken cardiac cells
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Research"
DOI: 10.1080/10715762.2017.1362106
Abstract: Abstract Uric acid (UA) is a potent scavenger of oxidants in most mammalian and avian species. The aim of this study was to obtain more comprehensive information regarding the relationship between different concentrations of UA… read more here.
Keywords: effect; oxidative damage; cardiac cells; chicken cardiac ... See more keywords
Overexpression of Ubiquinol-Cytochrome c Reductase Core Protein 1 May Protect H9c2 Cardiac Cells by Binding with Zinc
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/1314297
Abstract: In several recent studies, proteomics analyses suggest that increase of ubiquinol-cytochrome c reductase core protein 1 (UQCRC1) is cardio-protective. However, direct evidence for this effect has not yet been obtained. Thus, the current study aimed… read more here.
Keywords: h9c2 cardiac; cytochrome reductase; cardiac cells; ubiquinol cytochrome ... See more keywords
Reassessment of c-Kit in Cardiac Cells: A Complex Interplay Between Expression, Fate, and Function
Sign Up to like & getrecommendations! Published in 2018 at "Circulation Research"
DOI: 10.1161/circresaha.118.313215
Abstract: c-Kit (CD117) is a type III receptor tyrosine kinase that activates a downstream signaling cascade on binding to stem cell factor. Studies from the past 3 decades have demonstrated the expression of c-Kit in various… read more here.
Keywords: cardiac cells; adult; kit; kit cardiac ... See more keywords
Cell-Specific Mechanisms in the Heart of COVID-19 Patients
Sign Up to like & getrecommendations! Published in 2023 at "Circulation Research"
DOI: 10.1161/circresaha.123.321876
Abstract: From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19 abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis/myocarditis, ventricular dysfunction to acute heart failure, and even cardiogenic shock. Elevated serum cardiac… read more here.
Keywords: cell; covid; specific mechanisms; heart ... See more keywords
Canard analysis reveals why a large Ca2+ window current promotes early afterdepolarizations in cardiac myocytes
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1008341
Abstract: The pumping of blood through the heart is due to a wave of muscle contractions that are in turn due to a wave of electrical activity initiated at the sinoatrial node. At the cellular level,… read more here.
Keywords: cardiac cells; size window; window region; early afterdepolarizations ... See more keywords
Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.975931
Abstract: Chagas disease (CD), a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, is an important public health problem mainly in Latin America, leading to approximately 12,000 annual deaths. Current etiological treatment for CD… read more here.
Keywords: damage; combined treatment; trypanosoma cruzi; treatment ... See more keywords
Induction of Stem-Cell-Derived Cardiomyogenesis by Fibroblast Growth Factor 10 (FGF10) and Its Interplay with Cardiotrophin-1 (CT-1)
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11040534
Abstract: Simple Summary Cardiovascular diseases are worldwide one of the leading contributors of mortality, and among multiple therapeutic approaches, stem cell therapy has been introduced as a robust therapeutic strategy to alleviate related symptoms and restore… read more here.
Keywords: cell; stem cell; growth; fgf10 ... See more keywords
Extracellular vesicles in post-infarct ventricular remodelling.
Sign Up to like & getrecommendations! Published in 2018 at "Kardiologia polska"
DOI: 10.5603/kp.a2017.0178
Abstract: Post-infarct left ventricle remodelling (LVR) is defined as the structural and functional changes of the myocardium occurring after acute myocardial infarction (AMI) and leading to the loss of contractile tissue and subsequently to post-infarct heart… read more here.
Keywords: extracellular vesicles; cardiac cells; lvr; vesicles post ... See more keywords