Causal associations between sleep traits and four cardiac diseases: a Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.14016
Abstract: Previous studies investigated the associations between sleep traits and cardiac diseases, but the evidence for the causal inferences was unclear. This study aimed to explore the causal relationship between sleep and cardiac diseases by virtue… read more here.
Keywords: cardiac diseases; mendelian randomization; causal; study ... See more keywords
Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174566
Abstract: Since chemerin is an adipocytokine whose concentration in blood increases in the subjects with various cardiac diseases, chemerin may be involved in pathogenesis of cardiac diseases. In the present study, we examined the effects of… read more here.
Keywords: stimulates migration; cardiac diseases; chemerin stimulates; cardiac fibroblasts ... See more keywords
Bioinformatics analysis of non-synonymous variants in the KLF genes related to cardiac diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.01.085
Abstract: Kruppel-like Factors (KLF) are responsible for regulating many genes involved in physiological and pathological processes. They are characterized by three conserved zinc-fingers in the DNA-binding domain, wherein mutations could affect the binding efficiency and transcription… read more here.
Keywords: related cardiac; cardiac diseases; bioinformatics analysis; synonymous variants ... See more keywords
Dioscin and diosgenin: insights into their potential protective effects in cardiac diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114018
Abstract: BACKGROUND AND ETHNOPHARMACOLOGICAL RELEVANCE Dioscin and diosgenin derived from plants of the genus Dioscoreaceae such as D. nipponica and D. panthaica Prain et Burk. Were utilized as the main active ingredients of traditional herbal medicinal… read more here.
Keywords: research; diosgenin insights; diosgenin; dioscin diosgenin ... See more keywords
MicroRNA-133 mediates cardiac diseases: Mechanisms and clinical implications.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2017.03.037
Abstract: MicroRNAs (miRNAs) belong to the family of small non-coding RNAs that mediate gene expression by post-transcriptional regulation. Increasing evidence have demonstrated that miR-133 is enriched in muscle tissues and myogenic cells, and its aberrant expression… read more here.
Keywords: cardiac diseases; mediates cardiac; cardiac disorders; mir 133 ... See more keywords
Detection of genetic cardiac diseases by Ca2+ transient profiles using machine learning methods
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27695-5
Abstract: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have revolutionized cardiovascular research. Abnormalities in Ca2+ transients have been evident in many cardiac disease models. We have shown earlier that, by exploiting computational machine learning methods, normal… read more here.
Keywords: machine; machine learning; ca2 transients; genetic cardiac ... See more keywords
Novel cardiovascular magnetic resonance oxygenation approaches in understanding pathophysiology of cardiac diseases
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.12916
Abstract: Cardiovascular magnetic resonance imaging (CMR) permits accurate phenotyping of many cardiac diseases. CMR’s inherent advantages are its non‐invasive nature, lack of ionizing radiation and high accuracy and reproducibility. Furthermore, it is able to assess many… read more here.
Keywords: oxygenation; magnetic resonance; cardiac diseases; cmr ... See more keywords
Management of cardiac diseases in liver transplant recipients: Comprehensive review and multidisciplinary practice‐based recommendations
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.17049
Abstract: Cardiac diseases are one of the most common causes of morbidity and mortality following liver transplantation (LT). Prior studies have shown that cardiac diseases affect close to one‐third of liver transplant recipients (LTRs) long term… read more here.
Keywords: liver transplant; cardiac diseases; based recommendations; management ... See more keywords
Zebrafish Models of Cardiac Disease: From Fortuitous Mutants to Precision Medicine
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.122.320396
Abstract: Heart disease is the leading cause of death worldwide. Despite decades of research, most heart pathologies have limited treatments, and often the only curative approach is heart transplantation. Thus, there is an urgent need to… read more here.
Keywords: cardiac disease; disease; cardiac diseases; models cardiac ... See more keywords
Nucleolar stress: Friend or foe in cardiac function?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1045455
Abstract: Studies in the past decades have uncovered an emerging role of the nucleolus in stress response and human disease progression. The disruption of ribosome biogenesis in the nucleolus causes aberrant nucleolar architecture and function, termed… read more here.
Keywords: stress; function; nucleolar stress; cardiac diseases ... See more keywords
The crosstalk between STAT3 and microRNA in cardiac diseases and protection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.986423
Abstract: Signal transducer and activator of transcription 3 (STAT3), an important transcription factor and signaling molecule, play an important role in cardiac disease and protection. As a transcription factor, STAT3 upregulates anti-oxidative and anti-apoptotic genes but… read more here.
Keywords: cardiac disease; protection; cardiac diseases; stat3 ... See more keywords