Cardiac Fibrotic Remodeling on a Chip with Dynamic Mechanical Stimulation.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801146
Abstract: Cardiac tissue is characterized by being dynamic and contractile, imparting the important role of biomechanical cues in the regulation of normal physiological activity or pathological remodeling. However, the dynamic mechanical tension ability also varies due… read more here.
Keywords: cardiac fibrotic; phenotypic transition; dynamic mechanical; cfs ... See more keywords
miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway
Sign Up to like & getrecommendations! Published in 2017 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-017-0520-7
Abstract: BackgroundCardiac fibrosis play a key role in the atrial fibrillation pathogenesis but the underlying potential molecular mechanism is still understood. However, potential mechanisms for miR-21 upregulation and its role in cardiac fibrosis remain unclear. The… read more here.
Keywords: cardiac fibrotic; fibroblast proliferation; mir; proliferation ... See more keywords
Piezo1 Channel as a Potential Target for Hindering Cardiac Fibrotic Remodeling
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158065
Abstract: Fibrotic tissues share many common features with neoplasms where there is an increased stiffness of the extracellular matrix (ECM). In this review, we present recent discoveries related to the role of the mechanosensitive ion channel… read more here.
Keywords: hindering cardiac; cardiac fibrotic; piezo1 channel; target hindering ... See more keywords