Pleiotropic cardiac functions controlled by ischemia-induced lncRNA H19.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2020.07.001
Abstract: Myocardial ischemia induces a multifaceted remodeling process in the heart. Novel therapeutic entry points to counteract maladaptive signalling include the modulation of non-coding RNA molecules such as long non-coding RNA (lncRNA). We here questioned if… read more here.
Keywords: cardiac cell; lncrna h19; cardiac functions; ischemia ... See more keywords
Overexpression of long non‐coding RNA ANRIL promotes post‐ischaemic angiogenesis and improves cardiac functions by targeting Akt
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15343
Abstract: Angiogenesis is critical for re‐establishing the blood supply to the surviving myocardium after myocardial infarction (MI). Long non‐coding RNA ANRIL (lncRNA‐ANRIL) has been reported to regulate endothelial functions in cardiovascular diseases. This study was to… read more here.
Keywords: overexpression; lncrna anril; angiogenesis; anril ... See more keywords
In vivo Evaluation of Non-viral NICD Plasmid-Loaded PLGA Nanoparticles in Developing Zebrafish to Improve Cardiac Functions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.819767
Abstract: In the era of the advanced nanomaterials, use of nanoparticles has been highlighted in biomedical research. However, the demonstration of DNA plasmid delivery with nanoparticles for in vivo gene delivery experiments must be carefully tested… read more here.
Keywords: delivery; cardiac functions; improve cardiac; plga nanoparticles ... See more keywords
Modulations of Cardiac Functions and Pathogenesis by Reactive Oxygen Species and Natural Antioxidants
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DOI: 10.3390/antiox10050760
Abstract: Homeostasis in the level of reactive oxygen species (ROS) in cardiac myocytes plays a critical role in regulating their physiological functions. Disturbance of balance between generation and removal of ROS is a major cause of… read more here.
Keywords: reactive oxygen; oxygen species; natural antioxidants; cardiac functions ... See more keywords
An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.63481
Abstract: Rationale: Although a few injectable hydrogels have shown a reliable biosafety and a moderate promise in treating myocardial infarction (MI), the updated hydrogel systems with an on-demand biodegradation and multi-biofunctions to deliver therapeutic drug would… read more here.
Keywords: hif; mmp degradable; conductive hydrogel; degradable conductive ... See more keywords