Cardiac macrophages adopt profibrotic/M2 phenotype in infarcted hearts: Role of urokinase plasminogen activator.
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DOI: 10.1016/j.yjmcc.2016.05.016
Abstract: BACKGROUND Macrophages (mac) that over-express urokinase plasminogen activator (uPA) adopt a profibrotic M2 phenotype in the heart in association with cardiac fibrosis. We tested the hypothesis that cardiac macs are M2 polarized in infarcted mouse… read more here.
Keywords: phenotype; cardiac macs; urokinase plasminogen; heart ... See more keywords