Simultaneous determination of dynamic cardiac metabolism and function using PET/MRI
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-018-1287-7
Abstract: BackgroundCardiac metabolic changes in heart disease precede overt contractile dysfunction. However, metabolism and function are not typically assessed together in clinical practice. The purpose of this study was to develop a cardiac positron emission tomography/magnetic… read more here.
Keywords: simultaneous determination; metabolism; determination dynamic; cardiac metabolism ... See more keywords
Quadrupole Orbitrap Mass Spectrometer-Based Metabonomic Elucidation of Influences of Short-Term Di(2-ethylhexyl) phthalate Exposure on Cardiac Metabolism in Male Mice.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.8b00184
Abstract: Di(2-ethylhexyl) phthalate (DEHP) can cause severe environmental pollution. Effects of DEHP on cardiac metabolism have been reported, but its mechanism(s) of action is not fully clear. Here, we used high-resolution mass spectrometry for metabonomics and… read more here.
Keywords: cardiac metabolism; ethylhexyl phthalate; mass; dehp ... See more keywords
Cardiac metabolism as a driver and therapeutic target of myocardial infarction
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15180
Abstract: Reducing infarct size during a cardiac ischaemic‐reperfusion episode is still of paramount importance, because the extension of myocardial necrosis is an important risk factor for developing heart failure. Cardiac ischaemia‐reperfusion injury (IRI) is in principle… read more here.
Keywords: cardiac iri; metabolism; metabolic pathways; metabolism driver ... See more keywords
PGC-1: The Energetic Regulator in Cardiac Metabolism.
Sign Up to like & getrecommendations! Published in 2018 at "Current issues in molecular biology"
DOI: 10.21775/cimb.028.029
Abstract: The peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1s (PGC-1s) can induce the expression of several downstream genes that play pivotal roles in the regulation of mitochondrial biogenesis and metabolism in the heart. Moreover, PGC-1 signaling pathways… read more here.
Keywords: metabolism; pgc signaling; cardiac metabolism; pgc energetic ... See more keywords
In Vivo Magnetic Resonance Spectroscopy Methods for Investigating Cardiac Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12020189
Abstract: Magnetic resonance spectroscopy (MRS) is a non-invasive and non-ionizing technique, enabling in vivo investigation of cardiac metabolism in normal and diseased hearts. In vivo measurement tools are critical for studying mechanisms that regulate cardiac energy… read more here.
Keywords: magnetic resonance; resonance spectroscopy; metabolism; cardiac metabolism ... See more keywords