Engineering of cardiac microtissues by microfluidic cell encapsulation in thermoshrinking non-crosslinked PNIPAAm gels
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac73b5
Abstract: Multicellular agglomerates in form of irregularly shaped or spherical clusters can recapitulate cell–cell interactions and are referred to as microtissues. Microtissues gain increasing attention in several fields including cardiovascular research. Cardiac microtissues are evolving as… read more here.
Keywords: cell; microtissues microfluidic; cardiac microtissues; encapsulation ... See more keywords
From the Cover: High-Throughput Imaging of Cardiac Microtissues for the Assessment of Cardiac Contraction during Drug Discovery
Sign Up to like & getrecommendations! Published in 2017 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfw227
Abstract: Cardiotoxicity is a common cause of attrition in preclinical and clinical drug development. Current in vitro approaches have two main limitations, they either are limited to low throughput methods not amendable to drug discovery or… read more here.
Keywords: cardiac microtissues; throughput; cardiac contraction; drug ... See more keywords