Sea lamprey cardiac mitochondrial bioenergetics after exposure to TFM and its metabolites.
Sign Up to like & getrecommendations! Published in 2019 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2019.105380
Abstract: Population control of invasive sea lamprey relies heavily on lampricide treatment of infested streams. The lampricide 3-trifluoromethyl-4-nitrophenol (TFM) is thought to impair mitochondrial ATP production through uncoupling oxidative phosphorylation. However, the effect of TFM on… read more here.
Keywords: tfm; mitochondrial bioenergetics; sea lamprey; lamprey cardiac ... See more keywords
Chronic exposure to polluted urban air aggravates myocardial infarction by impaired cardiac mitochondrial function and dynamics.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.118677
Abstract: Air pollution exposure positively correlates with increased cardiovascular morbidity and mortality rates, mainly due to myocardial infarction (MI). Herein, we aimed to study the metabolic mechanisms underlying this association, focusing on the evaluation of cardiac… read more here.
Keywords: exposure; function; mice; air ... See more keywords
Effects of anticancer drugs on the cardiac mitochondrial toxicity and their underlying mechanisms for novel cardiac protective strategies.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119607
Abstract: Mitochondria are organelles that play a pivotal role in the production of energy in cells, and vital to the maintenance of cellular homeostasis due to the regulation of many biochemical processes. The heart contains a… read more here.
Keywords: drugs cardiac; mitochondrial toxicity; effects anticancer; toxicity ... See more keywords
Cardiac mitochondrial structure and function in tafazzin-knockdown mice.
Sign Up to like & getrecommendations! Published in 2018 at "Mitochondrion"
DOI: 10.1016/j.mito.2018.10.005
Abstract: Mutations in the tafazzin gene are the basis of Barth syndrome. The tafazzin protein is responsible for the synthesis of cardiolipin. Doxycycline-induced tafazzin-knockdown mice have been used as a model for Barth syndrome. In the… read more here.
Keywords: tafazzin knockdown; knockdown mice; barth syndrome; cardiac mitochondrial ... See more keywords
Cardiac mitochondrial dynamics: miR-mediated regulation during cardiac injury.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2017.07.003
Abstract: Mitochondrial integrity is indispensable for cardiac health. With the advent of modern imaging technologies, mitochondrial motility and dynamics within the cell are extensively studied. Terminally differentiated and well-structured cardiomyocytes depict little mitochondrial division and fusion,… read more here.
Keywords: mediated regulation; dynamics mir; cardiac mitochondrial; mitochondrial dynamics ... See more keywords
FGF21 protects against HFpEF by improving cardiac mitochondrial bioenergetics in mice
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-56885-9
Abstract: Fibroblast growth factor 21 (FGF21), a metabolic hormone with pleiotropic effects, is beneficial for various cardiac disorders. However, FGF21’s role in heart failure with preserved ejection fraction (HFpEF) remains unclear. Here, we show that elevated… read more here.
Keywords: hfpef improving; mitochondrial bioenergetics; cardiac mitochondrial; improving cardiac ... See more keywords
Cardiac Mitochondrial and Electrophysiological Changes in Transplanted Ovine Hearts Following Preservation by Hypothermic Oxygenated Perfusion
Sign Up to like & getrecommendations! Published in 2025 at "Transplantation"
DOI: 10.1097/tp.0000000000005490
Abstract: During heart transplantation (HTx), donor hearts are exposed to injury via brain death (BD) and cardiac preservation using static cold storage (SCS). Preservation using hypothermic oxygenated machine perfusion (HOPE) may reduce myocardial injury compared with… read more here.
Keywords: htx; hypothermic oxygenated; cardiac mitochondrial; donor ... See more keywords
Blocking the mineralocorticoid receptor prevents cardiac and mitochondrial dysfunction through the activation of NOX‐4 in female hormone deprivation rats
Sign Up to like & getrecommendations! Published in 2025 at "Acta Physiologica"
DOI: 10.1111/apha.70007
Abstract: Young women exhibit lower rates of cardiovascular disease (CVD) than age‐matched men, a protective effect often attributed to estrogen's influence on cardiac and mitochondrial function. The risk of CVD increases in post‐menopausal women, likely due… read more here.
Keywords: receptor prevents; mineralocorticoid receptor; mitochondrial dysfunction; cardiac mitochondrial ... See more keywords
Abstract 4141966: Myotonic Dystrophy type I (DM1) Impairs Cardiac Bioenergetics and Disrupts Cardiac Mitochondrial Fusion-Fission Dynamics
Sign Up to like & getrecommendations! Published in 2024 at "Circulation"
DOI: 10.1161/circ.150.suppl_1.4141966
Abstract: Background: DM1 is the commonest cause of adult-onset muscular dystrophy, affecting 1-in-2100 people in the U.S. DM1 is a (CTG)n trinucleotide repeat expansion disease in the 3’UTR of the DMPK gene. Once expressed, the repeat… read more here.
Keywords: heart; fission; dm1 mice; cardiac mitochondrial ... See more keywords
Abstract 276: Maternal High Fat, High Sucrose Diet-induced Cardiac Mitochondrial Abnormalities in the Offspring are Transmitted via the Oocyte Nucleus
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.276
Abstract: Introduction: Maternal obesity correlates with higher cardiovascular disease risk in human offspring. We found high fat, high sucrose (HF/HS) diet results in accretion of abnormal mitochondria in mouse oocytes, and chow-fed offspring of HF/HS-fed dams… read more here.
Keywords: fed dams; oocyte nucleus; cardiac mitochondrial; high fat ... See more keywords
50-OR: Recurrent Moderate Hypoglycemia (RH) Enhances Cardiac Mitochondrial Respiration in Diabetic Rats
Sign Up to like & getrecommendations! Published in 2025 at "Diabetes"
DOI: 10.2337/db25-50-or
Abstract: Introduction and Objective: Severe hypoglycemia can cause fatal arrhythmias, yet RH preconditioning reduces this risk (Reno et al. Diabetes 2017). We hypothesized that this protective effect in reducing arrhythmias is due to an RH preconditioning… read more here.
Keywords: diabetic rats; none; drh; cardiac mitochondrial ... See more keywords