STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development
Sign Up to like & getrecommendations! Published in 2023 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvad010
Abstract: Abstract Aims Retinoic acid (RA) signalling is essential for heart development, and dysregulation of the RA signalling can cause several types of cardiac outflow tract (OFT) defects, the most frequent congenital heart disease (CHD) in… read more here.
Keywords: development; human embryonic; outflow tract; stra6 ... See more keywords
Shorter periconception Maternal Telomere Length and the Risk of Congenital Cardiac Outflow Defects in the Offspring.
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DOI: 10.1111/eci.13784
Abstract: BACKGROUND Congenital cardiac outflow defects (COD) are the largest group of congenital heart defects, with ventricular septal defect (VSD) as the most prevalent phenotype. Increased maternal age, excessive oxidative stress and inflammation are involved in… read more here.
Keywords: risk; periconception maternal; telomere length; outflow defects ... See more keywords
Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract
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DOI: 10.7554/elife.57603
Abstract: The development of the cardiac outflow tract (OFT), which connects the heart to the great arteries, relies on a complex crosstalk between endothelial (ECs) and smooth muscle (SMCs) cells. Defects in OFT development can lead… read more here.
Keywords: tgf signaling; tgf; development cardiac; outflow tract ... See more keywords