Irisin promotes cardiac progenitor cell‐induced myocardial repair and functional improvement in infarcted heart
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27037
Abstract: Irisin, a newly identified hormone and cardiokine, is critical for modulating body metabolism. New evidence indicates that irisin protects the heart against myocardial ischemic injury. However, whether irisin enhances cardiac progenitor cell (CPC)‐induced cardiac repair… read more here.
Keywords: functional improvement; progenitor cell; cardiac progenitor; irisin ... See more keywords
Toll‐like receptors in the functional orientation of cardiac progenitor cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28738
Abstract: Cardiac progenitor cells (CPCs) have the potential to differentiate into several cell lineages with the ability to restore in cardiac tissue. Multipotency and self‐renewal activity are the crucial characteristics of CPCs. Also, CPCs have promising… read more here.
Keywords: toll like; progenitor cells; receptors functional; cardiac progenitor ... See more keywords
Epigenetic Priming of Human Pluripotent Stem Cell‐Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation
Sign Up to like & getrecommendations! Published in 2019 at "STEM CELLS"
DOI: 10.1002/stem.3021
Abstract: Human pluripotent stem cell‐derived cardiomyocytes (hPSC‐CMs) exhibit a fetal phenotype that limits in vitro and therapeutic applications. Strategies to promote cardiomyocyte maturation have focused interventions on differentiated hPSC‐CMs, but this study tests priming of early… read more here.
Keywords: hpsc cms; cardiomyocyte maturation; cardiac progenitor; pic ... See more keywords
Cardiac Progenitor Cell Extraction from Human Auricles.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6756-8_11
Abstract: For many years, myocardial tissue has been considered terminally differentiated and, thus, incapable of regenerating. Recent studies have shown, instead, that cardiomyocytes, at least in part, are slowly substituted by new cells originating by precursor… read more here.
Keywords: cell extraction; extraction human; progenitor cell; cardiac progenitor ... See more keywords
Isolation and Characterization of Cardiac Progenitor Cells.
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DOI: 10.1007/978-1-4939-9631-5_13
Abstract: Cardiac progenitor cells (CPCs) are gaining interest as a therapeutic option for the treatment of the heart. Due to the limited pool of CPCs residing in the heart, it is essential to isolate and expand… read more here.
Keywords: cardiac progenitor; isolation characterization; progenitor cells;
Cardiac Progenitor Cell-Derived Extracellular Vesicles: a Rising Star for Cardiac Repair and Regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-018-9862-5
Abstract: Cardiovascular diseases represent a significant cause of death and disability worldwide [1]. Myocardial infarction (MI), among other cardiovascular diseases, causes massive cardiomyocyte loss and scar formation in place of dead myocardial tissues, thus leading to… read more here.
Keywords: extracellular vesicles; progenitor cell; cardiac progenitor; progenitor ... See more keywords
p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo
Sign Up to like & getrecommendations! Published in 2017 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2017.01.028
Abstract: p53 is an important modulator of stem cell fate, but its role in cardiac progenitor cells (CPCs) is unknown. Here, we tested the effects of a single extra-copy of p53 on the function of CPCs… read more here.
Keywords: progenitor cells; diabetic heart; cpcs; cardiac progenitor ... See more keywords
Human cardiac progenitor cells with regenerative potential can be isolated and characterized from 3D-electro-anatomic guided endomyocardial biopsies.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2017.02.106
Abstract: AIMS In the present study, we aimed to develop a percutaneous approach and a reproducible methodology for the isolation and expansion of Cardiac Progenitor Cells (CPCs) from EndoMyocardial Biopsies (EMB) in vivo. Moreover, in an… read more here.
Keywords: methodology; progenitor cells; endomyocardial biopsies; cpcs ... See more keywords
Beta2‐adrenergic signaling affects the phenotype of human cardiac progenitor cells through EMT modulation
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DOI: 10.1016/j.phrs.2017.01.016
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Human cardiac progenitor cells (CPCs) offer great promises to cardiac cell therapy for heart failure. Many in vivo studies have shown their therapeutic benefits, paving the way for… read more here.
Keywords: modulation; progenitor cells; bgr; cardiac progenitor ... See more keywords
Generation of multipotent induced cardiac progenitor cells from mouse fibroblasts and potency testing in ex vivo mouse embryos
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DOI: 10.1038/nprot.2017.021
Abstract: Here we describe a protocol to generate expandable and multipotent induced cardiac progenitor cells (iCPCs) from mouse adult fibroblasts using forced expression of Mesp1, Tbx5, Gata4, Nkx2.5 and Baf60c (MTGNB) along with activation of Wnt… read more here.
Keywords: induced cardiac; progenitor cells; cardiac progenitor; multipotent induced ... See more keywords
CXCL6 is an important paracrine factor in the pro-angiogenic human cardiac progenitor-like cell secretome
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11976-6
Abstract: Studies in recent years have established that the principal effects in cardiac cell therapy are associated with paracrine/autocrine factors. We combined several complementary techniques to define human cardiac progenitor cell (CPC) secretome constituted by 914… read more here.
Keywords: cxcl6; cpc; cxcl6 important; cardiac progenitor ... See more keywords