Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS
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DOI: 10.1002/nbm.3992
Abstract: Hyperpolarized [1‐13C] pyruvate MRS can measure cardiac pyruvate dehydrogenase (PDH) flux in vivo through 13C‐label incorporation into bicarbonate. Using this technology, substrate availability as well as pathology have been shown to modulate PDH flux. Clinical… read more here.
Keywords: cardiac pyruvate; flux; pdh flux; pyruvate dehydrogenase ... See more keywords