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   Articles with "cardiac remodeling" as a keyword



Precisely Targeting Cardiac Remodeling Nanomachine for Restarting Healthy Heartbeat.

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recommendations! Published in 2025 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202503478

Abstract: Atrial fibrillation (AF) is a common arrhythmia that can cause serious symptoms and affect the quality of life of patients. Therefore, the treatment of AF has always faced challenges in the medical field. Here, Zn@Mg@MSNs@PEG… read more here.

Keywords: precisely targeting; targeting cardiac; nanomachine restarting; restarting healthy ... See more keywords

Impact of Dapagliflozin on cardiac remodeling in patients with chronic heart failure: DAPA-MODA study.

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recommendations! Published in 2023 at "European journal of heart failure"

DOI: 10.1002/ejhf.2884

Abstract: RATIONALE Dapagliflozin improves the prognosis of patients with heart failure (HF), regardless left ventricular ejection fraction (LVEF). However, its effect on cardiac remodeling parameters, specifically left atrial (LA) remodeling, is not well established. METHODS DAPA-MODA… read more here.

Keywords: heart failure; geometry; cardiac remodeling; heart ... See more keywords
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Nonalcoholic Fatty Liver Disease and Cardiac Remodeling Risk: Pathophysiological Mechanisms and Clinical Implications

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recommendations! Published in 2021 at "Hepatology"

DOI: 10.1002/hep.32072

Abstract: With dramatic increases in obesity and diabetes, nonalcoholic fatty liver disease (NAFLD) has become one of the most prevalent chronic liver diseases, affecting approximately one-quarter of adults worldwide. It is noteworthy that patients with NAFLD… read more here.

Keywords: liver disease; cardiac remodeling; nonalcoholic fatty; fatty liver ... See more keywords
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Myocardial proteases and cardiac remodeling

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recommendations! Published in 2017 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.25884

Abstract: Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need to further investigate the… read more here.

Keywords: proteases cardiac; cardiac remodeling; physiology; myocardial proteases ... See more keywords
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Carotid baroreceptor stimulation prevents oxidative stress by inhibiting MAO‐A and prevents cardiac remodeling in obese rats

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recommendations! Published in 2023 at "Obesity"

DOI: 10.1002/oby.23729

Abstract: Sympathetic nervous system overactivation and abnormal lipid metabolism are featured in obesity and may lead to cardiac remodeling. The effects of carotid baroreceptor stimulation (CBS) on cardiac remodeling in obese rats and the underlying mechanisms… read more here.

Keywords: obese rats; cardiac remodeling; remodeling obese; baroreceptor stimulation ... See more keywords

Portulaca oleracea L. Extract and Its Alkaloid Oleracein E Alleviates Cardiac Remodeling and Heart Failure in Mice by Targeting STAT2 Through the MAPK Signaling Inflammatory Pathway

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recommendations! Published in 2025 at "Phytotherapy Research"

DOI: 10.1002/ptr.8501

Abstract: Hypertensive heart failure pathogenesis involves angiotensin II (Ang II)‐mediated mechanisms through both hemodynamic overload and direct cellular signaling pathways. This study investigates the therapeutic potential of Portulaca oleracea L. (POL) extract and its active constituent… read more here.

Keywords: heart; mapk signaling; cardiac remodeling; pathway ... See more keywords

Vinpocetine Attenuates Pathological Cardiac Remodeling by Inhibiting Cardiac Hypertrophy and Fibrosis

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recommendations! Published in 2017 at "Cardiovascular Drugs and Therapy"

DOI: 10.1007/s10557-017-6719-0

Abstract: PurposePathological cardiac remodeling, characterized by cardiac hypertrophy and fibrosis, is a pathological feature of many cardiac disorders that leads to heart failure and cardiac arrest. Vinpocetine, a derivative of the alkaloid vincamine, has been used… read more here.

Keywords: cardiac hypertrophy; vinpocetine; fibrosis; cardiac remodeling ... See more keywords

Effects of the chymase inhibitor fulacimstat on adverse cardiac remodeling after acute myocardial infarction-Results of the Chymase Inhibitor in Adverse Remodeling after Myocardial Infarction (CHIARA MIA) 2 trial.

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recommendations! Published in 2020 at "American heart journal"

DOI: 10.1016/j.ahj.2020.01.012

Abstract: BACKGROUND Adverse cardiac remodeling is a major risk factor for the development of post myocardial infarction (MI) heart failure (HF). This study investigates the effects of the chymase inhibitor fulacimstat on adverse cardiac remodeling after… read more here.

Keywords: adverse cardiac; chymase inhibitor; cardiac remodeling; infarction ... See more keywords
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Fetal cardiac remodeling associated with preeclampsia and fetal growth restriction: 202

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recommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"

DOI: 10.1016/j.ajog.2018.11.223

Abstract: (Figure 1). In SGA and FGR placentas, there is evidence of reduced telomerase activity and subsequent telomere shortening that could activate cell senescence and p53 (Figure 2). CONCLUSION: A comprehensive assessment demonstrated accelerated placental aging… read more here.

Keywords: remodeling associated; preeclampsia fetal; associated preeclampsia; cardiac remodeling ... See more keywords

Racial and Ethnic Differences in Biomarkers, Health Status, and Cardiac Remodeling in Patients with Heart Failure with Reduced Ejection Fraction Treated with Sacubitril/valsartan

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recommendations! Published in 2020 at "Journal of Cardiac Failure"

DOI: 10.1016/j.cardfail.2020.09.045

Abstract: Background Among patients with heart failure and reduced ejection fraction (HFrEF, left ventricular [LV] EF ≤40%), sacubitril/valsartan (S/V) has favorable effects on biomarkers, health status, and reverse cardiac remodeling. Objectives To determine racial and ethnic… read more here.

Keywords: health status; non hispanic; cardiac remodeling; failure ... See more keywords

Atrial Natriuretic Peptide Mediates Reverse Cardiac Remodeling During Treatment with Sacubitril/Valsartan in Patients with Heart Failure with Reduced Ejection Fraction

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recommendations! Published in 2020 at "Journal of Cardiac Failure"

DOI: 10.1016/j.cardfail.2020.09.048

Abstract: Introduction Sacubitril/valsartan (S/V) promotes reverse cardiac remodeling in patients with HFrEF. Neprilysin inhibition results in increase of several vasoactive peptides that may mediate effects of S/V, however its effects on atrial natriuretic peptide (ANP) are… read more here.

Keywords: natriuretic peptide; sacubitril valsartan; cardiac remodeling; reverse cardiac ... See more keywords