Impact of Dapagliflozin on cardiac remodeling in patients with chronic heart failure: DAPA-MODA study.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of heart failure"
DOI: 10.1002/ejhf.2884
Abstract: RATIONALE Dapagliflozin improves the prognosis of patients with heart failure (HF), regardless left ventricular ejection fraction (LVEF). However, its effect on cardiac remodeling parameters, specifically left atrial (LA) remodeling, is not well established. METHODS DAPA-MODA… read more here.
Keywords: heart failure; geometry; cardiac remodeling; heart ... See more keywords
Nonalcoholic Fatty Liver Disease and Cardiac Remodeling Risk: Pathophysiological Mechanisms and Clinical Implications
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32072
Abstract: With dramatic increases in obesity and diabetes, nonalcoholic fatty liver disease (NAFLD) has become one of the most prevalent chronic liver diseases, affecting approximately one-quarter of adults worldwide. It is noteworthy that patients with NAFLD… read more here.
Keywords: liver disease; cardiac remodeling; nonalcoholic fatty; fatty liver ... See more keywords
Myocardial proteases and cardiac remodeling
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25884
Abstract: Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need to further investigate the… read more here.
Keywords: proteases cardiac; cardiac remodeling; physiology; myocardial proteases ... See more keywords
Carotid baroreceptor stimulation prevents oxidative stress by inhibiting MAO‐A and prevents cardiac remodeling in obese rats
Sign Up to like & getrecommendations! Published in 2023 at "Obesity"
DOI: 10.1002/oby.23729
Abstract: Sympathetic nervous system overactivation and abnormal lipid metabolism are featured in obesity and may lead to cardiac remodeling. The effects of carotid baroreceptor stimulation (CBS) on cardiac remodeling in obese rats and the underlying mechanisms… read more here.
Keywords: obese rats; cardiac remodeling; remodeling obese; baroreceptor stimulation ... See more keywords
Vinpocetine Attenuates Pathological Cardiac Remodeling by Inhibiting Cardiac Hypertrophy and Fibrosis
Sign Up to like & getrecommendations! Published in 2017 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-017-6719-0
Abstract: PurposePathological cardiac remodeling, characterized by cardiac hypertrophy and fibrosis, is a pathological feature of many cardiac disorders that leads to heart failure and cardiac arrest. Vinpocetine, a derivative of the alkaloid vincamine, has been used… read more here.
Keywords: cardiac hypertrophy; vinpocetine; fibrosis; cardiac remodeling ... See more keywords
Effects of the chymase inhibitor fulacimstat on adverse cardiac remodeling after acute myocardial infarction-Results of the Chymase Inhibitor in Adverse Remodeling after Myocardial Infarction (CHIARA MIA) 2 trial.
Sign Up to like & getrecommendations! Published in 2020 at "American heart journal"
DOI: 10.1016/j.ahj.2020.01.012
Abstract: BACKGROUND Adverse cardiac remodeling is a major risk factor for the development of post myocardial infarction (MI) heart failure (HF). This study investigates the effects of the chymase inhibitor fulacimstat on adverse cardiac remodeling after… read more here.
Keywords: adverse cardiac; chymase inhibitor; cardiac remodeling; infarction ... See more keywords
Fetal cardiac remodeling associated with preeclampsia and fetal growth restriction: 202
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2018.11.223
Abstract: (Figure 1). In SGA and FGR placentas, there is evidence of reduced telomerase activity and subsequent telomere shortening that could activate cell senescence and p53 (Figure 2). CONCLUSION: A comprehensive assessment demonstrated accelerated placental aging… read more here.
Keywords: remodeling associated; preeclampsia fetal; associated preeclampsia; cardiac remodeling ... See more keywords
Racial and Ethnic Differences in Biomarkers, Health Status, and Cardiac Remodeling in Patients with Heart Failure with Reduced Ejection Fraction Treated with Sacubitril/valsartan
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2020.09.045
Abstract: Background Among patients with heart failure and reduced ejection fraction (HFrEF, left ventricular [LV] EF ≤40%), sacubitril/valsartan (S/V) has favorable effects on biomarkers, health status, and reverse cardiac remodeling. Objectives To determine racial and ethnic… read more here.
Keywords: health status; non hispanic; cardiac remodeling; failure ... See more keywords
Atrial Natriuretic Peptide Mediates Reverse Cardiac Remodeling During Treatment with Sacubitril/Valsartan in Patients with Heart Failure with Reduced Ejection Fraction
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2020.09.048
Abstract: Introduction Sacubitril/valsartan (S/V) promotes reverse cardiac remodeling in patients with HFrEF. Neprilysin inhibition results in increase of several vasoactive peptides that may mediate effects of S/V, however its effects on atrial natriuretic peptide (ANP) are… read more here.
Keywords: natriuretic peptide; sacubitril valsartan; cardiac remodeling; reverse cardiac ... See more keywords
Mitochondria in Pathological Cardiac Remodeling.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in physiology"
DOI: 10.1016/j.cophys.2022.100489
Abstract: Adverse cardiac remodeling is often precipitated by chronic stress or injury inflicted upon the heart during the progression of cardiovascular diseases. Mitochondria play an important role in the cardiomyocyte response to stress by serving as… read more here.
Keywords: cardiac remodeling; mitochondria pathological; physiology; pathological cardiac ... See more keywords
Pinocembrin mediates antiarrhythmic effects in rats with isoproterenol-induced cardiac remodeling.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2022.174799
Abstract: BACKGROUND High levels of circulating catecholamines are related to raise risk of cardiac arrhythmias. In addition, our recent studies have suggested that pinocembrin could decrease the susceptibility to arrhythmias in several rat models, including chronic… read more here.
Keywords: isoproterenol induced; pinocembrin mediates; cardiac remodeling; mediates antiarrhythmic ... See more keywords