Cardiac remodelling – Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology
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DOI: 10.1002/ejhf.2493
Abstract: Cardiac remodelling refers to changes in left ventricular structure and function over time, with a progressive deterioration that may lead to heart failure (HF) development (adverse remodelling) or vice versa a recovery (reverse remodelling) in… read more here.
Keywords: cardiology; heart failure; cardiac remodelling; part ... See more keywords
Molecular imaging of cardiac remodelling after myocardial infarction
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DOI: 10.1007/s00395-018-0668-z
Abstract: Myocardial infarction and subsequent heart failure is a major health burden associated with significant mortality and morbidity in western societies. The ability of cardiac tissue to recover after myocardial infarction is affected by numerous complex… read more here.
Keywords: cardiac remodelling; myocardial infarction; imaging cardiac; infarction ... See more keywords
HDAC inhibitors and cardioprotection: Homing in on a mechanism of action
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.01.015
Abstract: Histone deacetylases (HDACs) are epigenetic regulators with imporConsistent with the observed reductions in apoptotic, oxidative stress tant roles in numerous cellular processes. The HDAC superfamily is divided into four classes based on function and sequence… read more here.
Keywords: vpa; cardiac remodelling; hdac inhibitors; infarct size ... See more keywords
Adipose tissue dysfunction, inflammation, and insulin resistance: alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case–control study
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01741-9
Abstract: Cardiovascular diseases are the leading cause of death in schizophrenia. Patients with schizophrenia show evidence of concentric cardiac remodelling (CCR), defined as an increase in left-ventricular mass over end-diastolic volumes. CCR is a predictor of… read more here.
Keywords: dysfunction; cardiac remodelling; schizophrenia multimodal; schizophrenia ... See more keywords
Mechanisms contributing to cardiac remodelling.
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DOI: 10.1042/cs20171167
Abstract: Cardiac remodelling is classified as physiological (in response to growth, exercise and pregnancy) or pathological (in response to inflammation, ischaemia, ischaemia/reperfusion (I/R) injury, biomechanical stress, excess neurohormonal activation and excess afterload). Physiological remodelling of the… read more here.
Keywords: response; mechanisms contributing; cardiac remodelling; stress ... See more keywords
Potential adverse cardiac remodelling in highly trained athletes: still unknown clinical significance
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Sport Science"
DOI: 10.1080/17461391.2018.1484174
Abstract: Abstract Moderate endurance exercise has long been considered an essential element to maintain cardiovascular health, and sedentary behaviour in the general population has been related to a significant increase in all-causes of mortality, cardiovascular disease… read more here.
Keywords: cardiac remodelling; clinical significance; exercise; potential adverse ... See more keywords
Cardiac remodelling in the highest city in the world: Effects of altitude and chronic mountain sickness.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of preventive cardiology"
DOI: 10.1093/eurjpc/zwac166
Abstract: AIMS A unique Andean population lives in the highest city of the world (La Rinconada, 5,100 m, Peru) and frequently develops a maladaptive syndrome, termed chronic mountain sickness (CMS). Both extreme altitude and CMS are a… read more here.
Keywords: city world; highest city; cms; chronic mountain ... See more keywords
Tumour necrosis factor receptor-associated factors: interacting protein with forkhead-associated domain inhibition decreases inflammatory cell infiltration and cardiac remodelling after acute myocardial infarction.
Sign Up to like & getrecommendations! Published in 2020 at "Interactive cardiovascular and thoracic surgery"
DOI: 10.1093/icvts/ivaa060
Abstract: OBJECTIVES Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide. Post-AMI cardiac remodelling is closely related to the prognosis of AMI. The excess inflammatory responses could promote cardiac remodelling. Tumour necrosis… read more here.
Keywords: cardiac remodelling; tumour necrosis; factor; ami ... See more keywords
MO097BETA BLOCKER PREVENTS CARDIAC MOLECULAR AND MORPHOLOGICAL REMODELLING IN EXPERIMENTAL URAEMIA
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DOI: 10.1093/ndt/gfab106.006
Abstract: Fifty years of heart failure research has shown that pathological cardiac remodelling forms a vicious cycle with myocardial dysfunction leading to progressive heart failure (HF) [Circulation, 102 IV14-23, 2000]. Fetal gene induction is associated with… read more here.
Keywords: blocker; beta; cardiac remodelling; blocker therapy ... See more keywords
Atorvastatin reverses high cholesterol‐induced cardiac remodelling and regulates mitochondrial quality‐control in a cholesterol‐independent manner: An experimental study
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13507
Abstract: Mitochondria are key regulators of cell fate, maintaining self‐stability by a fine‐tuned quality‐control network including mitophagy, biogenesis, fission and fusion processes. Myocardial mitochondria can be impaired by hypercholesterolemia. Statins, such as atorvastatin, are considered the… read more here.
Keywords: cardiac remodelling; atorvastatin; cholesterol; quality control ... See more keywords
Cardiac remodelling in association with left ventricular dyssynchrony and systolic dysfunction in patients with coronary artery disease
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DOI: 10.1111/cpf.12780
Abstract: In patients with coronary artery disease (CAD), ischaemic cardiomyopathy may result in progressive cardiac remodelling and left ventricular (LV) dysfunction. Myocardial perfusion imaging (MPI) can be used to quantify LV size and shape, mechanical dyssynchrony… read more here.
Keywords: artery disease; patients coronary; coronary artery; left ventricular ... See more keywords