Promising approach for the preclinical assessment of cardiac risks using left ventricular pressure-volume loop analyses in anesthetized monkeys.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2016.10.004
Abstract: INTRODUCTION Load-independent cardiac parameters obtained from the ventricular pressure-volume relationship are recognized as gold standard indexes for evaluating cardiac inotropy. In this study, for better analyses of cardiac risks, load-independent pressure-volume loop parameters were assessed… read more here.
Keywords: pressure; ventricular pressure; pressure volume; cardiac risks ... See more keywords
Etomidate enabled electroconvulsive therapy without suppressing adrenocortical function in a case with difficulties in inducing seizures by conventional methods
Sign Up to like & getrecommendations! Published in 2020 at "Psychiatry and Clinical Neurosciences"
DOI: 10.1111/pcn.13139
Abstract: secutory delusions and hallucinatory behaviors. Risperidone was titrated to 1.5 mg/day, and she achieved full remission within the next 2 weeks. Repeat echocardiogram showed ejection fraction of 65% and no regional wall motion abnormalities. Outpatient… read more here.
Keywords: enabled electroconvulsive; etomidate enabled; case; electroconvulsive therapy ... See more keywords
Updated insights on cardiac risks of CD19-directed chimeric antigen receptor T-cell therapy: a pharmacovigilance study.
Sign Up to like & getrecommendations! Published in 2023 at "Immunotherapy"
DOI: 10.2217/imt-2022-0145
Abstract: Aim: Comprehensively characterize the cardiotoxicity of CD19-directed chimeric antigen receptor T-cell (CAR-T) products. Materials & methods: Data between 2017 and 2021 in the US FDA's Adverse Event Reporting System database were utilized. Disproportionality was measured using reporting… read more here.
Keywords: directed chimeric; antigen receptor; receptor cell; chimeric antigen ... See more keywords