Cardiac Specific IP3R Over-Expression: IP3ICR Contribution in Ca2+ Signaling
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2919
Abstract: Inositol-1,4,5-trisphosphate (IP3) is a second messenger produced upon agonist binding to a G-protein coupled receptor (GPCR) and subsequently triggers SR-Ca2+ release through openings of IP3 receptors (IP3Rs). In cardiac muscle, IP3R type 2 (IP3R2) is… read more here.
Keywords: ip3r; contribution ca2; ca2; cardiac specific ... See more keywords
Novel Invasive and Noninvasive Cardiac-Specific Biomarkers in Obesity and Cardiovascular Diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2019.0073
Abstract: Cardiovascular disease (CVD) is the leading cause of fatality and disability worldwide regardless of gender. Obesity has reached epidemic proportions in population across different regions. According to epidemiological studies, CVD risk markers in childhood obesity… read more here.
Keywords: specific biomarkers; invasive noninvasive; risk factors; cardiac specific ... See more keywords
Overexpression of Cardiac-Specific Kinase TNNI3K Promotes Mouse Embryonic Stem Cells Differentiation into Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000456400
Abstract: Backgroud/Aims: The biological function of cardiac troponin I-interacting kinase (TNNI3K), a cardiac-specific functional kinase, is largely unknown. We investigated the effect of human TNNI3K (hTNNI3K) on the differentiation of mouse embryonic stem cells (mESCs) into… read more here.
Keywords: kinase tnni3k; tnni3k; cardiac specific; overexpression ... See more keywords
Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation
Sign Up to like & getrecommendations! Published in 2020 at "Cardiology"
DOI: 10.1159/000505316
Abstract: Introduction: Ventricular arrhythmia is the most important risk factor for sudden cardiac death (SCD) after acute myocardial infarction (MI) worldwide. However, the molecular mechanisms underlying these arrhythmias are complex and not completely understood. Objective: Here,… read more here.
Keywords: ventricular arrhythmias; overexpression; cardiac specific; cav3 ... See more keywords
Expression of Cardiac Specific Cell Marker in Ex Vivo Differentiated Canine iPSC
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Animal Research"
DOI: 10.18805/ijar.b-3829
Abstract: Induced Pluripotent stem cells (iPSC) have a high ability to renew and differentiate themselves into various lineages and as vehicles of cell based therapy. Stem cell can differentiate under appropriate in vitro and in vivo… read more here.
Keywords: expression cardiac; differentiated canine; canine ipsc; expression ... See more keywords
The risks and trends of cardiac-specific mortality associated with chemotherapy or radiotherapy in a large cohort of non-elderly patients with non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2021 at "Translational Cancer Research"
DOI: 10.21037/tcr-20-2981
Abstract: Background Anticancer treatment-related heart events is a major concern. However, the frequent occurrence time of cardiac death and the association between cardiac-specific mortality (CSM) and various lung lobes among non-elderly non-small cell lung cancer (NSCLC)… read more here.
Keywords: cancer; lung; specific mortality; cardiac specific ... See more keywords
Cardiac-Specific Deletion of Pyruvate Dehydrogenase Impairs Glucose Oxidation Rates and Induces Diastolic Dysfunction
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2018.00017
Abstract: Obesity and type 2 diabetes (T2D) increase the risk for cardiomyopathy, which is the presence of ventricular dysfunction in the absence of underlying coronary artery disease and/or hypertension. As myocardial energy metabolism is altered during… read more here.
Keywords: oxidation; mice; glucose oxidation; cardiac specific ... See more keywords
Myoglobin Offers Higher Accuracy Than Other Cardiac-Specific Biomarkers for the Prognosis of COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.686328
Abstract: Although sporadic studies have shown that myoglobin may have better prognostic performance than other cardiac markers in COVID-19, a comprehensive comparative study is lacking. Herein, we retrospectively analyzed the clinical and laboratory data of COVID-19… read more here.
Keywords: myoglobin offers; specific biomarkers; accuracy cardiac; myoglobin ... See more keywords
Effect of radiotherapy on cardiac-specific death in patients with non-malignant tumors of central nervous system and related clinical features
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.991621
Abstract: Importance Cardiac-specific death from radiation caused by radiation therapy (RT) in patients with malignant tumors has received extensive attention, however, little is known regarding the potential cardiotoxic effects of RT in patients with non-malignant tumors.… read more here.
Keywords: specific death; malignant tumors; death; patients non ... See more keywords
Effects of different types of radiation therapy on cardiac-specific death in patients with thyroid malignancy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.996732
Abstract: Radiation therapy (RT) is one of the common and widely used treatment method for thyroid tumors. Considering that the thyroid is located close to the heart, the radiation generated during the treatment of thyroid tumors… read more here.
Keywords: cardiac specific; specific death; radiation therapy; patients thyroid ... See more keywords
An Adult Mouse Model of Dilated Cardiomyopathy Caused by Inducible Cardiac-Specific Bis Deletion
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22031343
Abstract: BCL-2 interacting cell death suppressor (BIS) is a multifunctional protein that has been implicated in cancer and myopathy. Various mutations of the BIS gene have been identified as causative of cardiac dysfunction in some dilated… read more here.
Keywords: dcm; bis; mice; dilated cardiomyopathy ... See more keywords