Age-related difference of longitudinal associations of early/late cardiac systolic load with decline of preserved cardiac systolic function in Japanese men
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.1136
Abstract: This prospective observational study was conducted to examine the longitudinal associations of early/late cardiac systolic load (ESL/LSL) with decline of preserved cardiac systolic function, and also to examine the age-related differences in their associations. In… read more here.
Keywords: systolic function; age related; age; cardiac systolic ... See more keywords
The Novel Cardiac Myosin Activator Danicamtiv Improves Cardiac Systolic Function at the Expense of Diastolic Dysfunction In Vitro and In Vivo: Implications for Clinical Applications
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010446
Abstract: Recent cardiotropic drug developments have focused on cardiac myofilaments. Danicamtiv, the second direct myosin activator, has achieved encouraging results in preclinical and clinical studies, thus implicating its potential applicability in the treatment of heart failure… read more here.
Keywords: cardiac systolic; myosin activator; diastolic dysfunction; danicamtiv improves ... See more keywords
Excitation-Contraction Coupling Time is More Sensitive in Evaluating Cardiac Systolic Function
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DOI: 10.4103/0366-6999.237395
Abstract: Background: Pressure overload-induced myocardial hypertrophy is a key step leading to heart failure. Previous cellular and animal studies demonstrated that deteriorated excitation–contraction coupling occurs as early as the compensated stage of hypertrophy before the global… read more here.
Keywords: coupling time; systolic function; evaluating cardiac; time ... See more keywords
Longitudinal Association of Arterial Stiffness and Pressure Wave Reflection with Decline of the Cardiac Systolic Performance in Healthy Men.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of atherosclerosis and thrombosis"
DOI: 10.5551/jat.63099
Abstract: AIMS This prospective observational study aimed to examine the individual longitudinal associations of the increases in the arterial stiffness and pressure wave reflection with the decline in the cardiac systolic performance during the study period… read more here.
Keywords: pressure wave; period; decline cardiac; cardiac systolic ... See more keywords