Cardiac serum marker alterations after intraoperative radiotherapy with low-energy x-rays in early breast cancer as an indicator of possible cardiac toxicity
Sign Up to like & getrecommendations! Published in 2020 at "Strahlentherapie Und Onkologie"
DOI: 10.1007/s00066-020-01671-3
Abstract: Purpose To assess acute cardiac toxicity caused by intraoperative radiotherapy (IORT) with low-energy x‑rays for early breast cancer. Methods We prospectively analyzed pre- and postoperative troponin I and NT-proBNP in 94 women who underwent breast-conserving surgery between… read more here.
Keywords: energy rays; breast cancer; low energy; cardiac toxicity ... See more keywords
Investigation of the ameliorative effects of baicalin against arsenic trioxide-induced cardiac toxicity in mice.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108024
Abstract: Baicalin (BA), a kind of flavonoids compound, comes from Scutellaria baicalensis Georgi (a kind of perennial herb) and has beneficial effects on the cardiovascular system through anti-oxidant, anti-inflammation, and anti-apoptosis actions. However, the therapeutic effects… read more here.
Keywords: induced cardiac; arsenic trioxide; ato induced; cardiac toxicity ... See more keywords
Analysis of cardiac toxicity after definitive chemoradiotherapy for esophageal cancer using a biological dose–volume histogram
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rraa001
Abstract: Abstract This study aimed to evaluate the relationship between cardiac toxicity after definitive chemoradiotherapy (CRT) for esophageal cancer and the dose–volume histogram (DVH) of organs at risk (OARs) [using biological effective dose (BED)]. We analyzed… read more here.
Keywords: dose volume; esophageal cancer; volume histogram; cardiac toxicity ... See more keywords
Abstract 4416: IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy
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DOI: 10.1158/1538-7445.am2023-4416
Abstract: Background: Immune checkpoint blockers (ICBs) have revolutionized cancer treatment, but they are often associated with severe immune related adverse events (irAEs). These severe irAEs are more often seen in patients with obesity or concomitantly treated… read more here.
Keywords: prevents cardiac; blockade; cardiac toxicity; blockade prevents ... See more keywords
Prediction of Cardiac Toxicity by Measurement of Coronary Artery Calcium Scoring Method Using Chest Computed Tomography in Early Breast Cancer Patients Treated with Trastuzumab
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DOI: 10.1159/000527683
Abstract: Background: In human epidermal growth factor receptor 2 (HER2)-positive early stage breast cancer, prediction of trastuzumab-related cardiac toxicity remains a challenge. The coronary calcium artery (CAC) reflects the total coronary plaque burden, which predicts the… read more here.
Keywords: cardiac toxicity; breast cancer; breast; prediction ... See more keywords
Incidence, Risk Factors and Outcomes of Cardiac Toxicity in Haploidentical Peripheral Stem Cell Transplantation with High Dose Cyclophosphamide
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DOI: 10.1182/blood-2020-141416
Abstract: Introduction: Haploidentical donor transplant (HIDT) with high dose post-transplant cyclophosphamide (PTcy) has shown promising results in terms of GVHD and survival. PTcy when given on day +3 and +4 is associated with considerable morbidity. In… read more here.
Keywords: stem cell; toxicity; cardiac toxicity; risk factors ... See more keywords
Incidence, risk factors, and impact of early cardiac toxicity after allogeneic hematopoietic cell transplant
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DOI: 10.1182/bloodadvances.2022008792
Abstract: Key Points • Using PTCY for GVHD prevention and TBI-based conditioning regimens increased the risk for early cardiac toxicity in adults undergoing allo-HCT. read more here.
Keywords: cardiac toxicity; incidence risk; risk factors; early cardiac ... See more keywords
Ratiometric Delivery of Mitoxantrone and Berberine Co-encapsulated Liposomes to Improve Antitumor Efficiency and Decrease Cardiac Toxicity
Sign Up to like & getrecommendations! Published in 2021 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01910-x
Abstract: Combination therapy is one of the most common clinical practices in the treatment of malignancies. Synergistic effects, however, are produced only when optimal ratios of combined drugs were delivered to tumor cells. Thus, carriers co-encapsulating… read more here.
Keywords: cardiac toxicity; delivery; encapsulated liposomes; berberine ... See more keywords
Clinical and genetic predictions of early-onset cardiac toxicity in adjuvant chemotherapy for breast cancer.
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DOI: 10.2217/fon-2021-1021
Abstract: Aim: To identify clinical and genetic variants associated with early-onset cardiac toxicity with a low cumulative dose of chemotherapy drugs in breast cancer. Methods: A total of 388 recruited patients completed routine blood, liver and… read more here.
Keywords: onset cardiac; early onset; toxicity; cardiac toxicity ... See more keywords
Hypofractionated Whole-Breast Irradiation Focus on Coronary Arteries and Cardiac Toxicity—A Narrative Review
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DOI: 10.3389/fonc.2022.862819
Abstract: Breast cancer is the most common cancer among women worldwide, which is often treated with radiotherapy. Whole breast irradiation (WBI) is one of the most common types of irradiation. Hypo-fractionated WBI (HF-WBI) reduces the treatment… read more here.
Keywords: cardiac toxicity; breast irradiation; heart; irradiation ... See more keywords
Monoclonal Antibody-Based Immunotherapy and Its Role in the Development of Cardiac Toxicity
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DOI: 10.3390/cancers13010086
Abstract: Simple Summary The application of immunotherapies to treat cancer patients has significantly improved over the last two decades and extended many patients’ life spans. Monoclonal antibodies are synthetic proteins employed as immunotherapies to treat and… read more here.
Keywords: immunotherapy; cardiac toxicity; biology; cancer ... See more keywords