Mutual Antagonism of Hypoxia-Inducible Factor Isoforms in Cardiac, Vascular, and Renal Disorders
Sign Up to like & getrecommendations! Published in 2020 at "JACC: Basic to Translational Science"
DOI: 10.1016/j.jacbts.2020.05.006
Abstract: Highlights • HIF-1α and HIF-2α promote cellular adaptation to acute hypoxia, but during prolonged activation, these isoforms exert mutually antagonistic effects on the redox state and on proinflammatory pathways.• Imbalances in HIF-1α and HIF-2α may… read more here.
Keywords: renal disorders; cardiac vascular; mutual antagonism; antagonism hypoxia ... See more keywords
Caveolin as a Novel Potential Therapeutic Target in Cardiac and Vascular Diseases: A Mini Review
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DOI: 10.14336/ad.2019.09603
Abstract: Caveolin, a structural protein of caveolae, play roles in the regulation of endothelial function, cellular lipid homeostasis, and cardiac function by affecting the activity and biogenesis of nitric oxide, and by modulating signal transduction pathways… read more here.
Keywords: review; caveolin; caveolin novel; cardiac vascular ... See more keywords
Cardiac and vascular causes of persistent fever: A systematic review.
Sign Up to like & getrecommendations! Published in 2019 at "Reviews in cardiovascular medicine"
DOI: 10.31083/j.rcm.2019.04.565
Abstract: Fever of unknown origin refers to a prolonged fever with an unknown cause despite adequate medical evaluations. This condition often leads to unnecessary extensive laboratory work-ups and antimicrobial therapies. The atypical presentations often cause a… read more here.
Keywords: cardiac vascular; cardiac surgical; unknown origin; vascular causes ... See more keywords
Cardiac and Vascular Remodeling After 6 Months of Therapy With Sacubitril/Valsartan: Mechanistic Insights From Advanced Echocardiographic Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.883769
Abstract: Background Effects of Sacubitril/Valsartan (S/V) on left ventricular (LV) mechanics and ventricular-arterial coupling in patients with heart failure with reduced ejection fraction (HFrEF) are not completely understood. The aim of this study was to evaluate… read more here.
Keywords: hdfs; sacubitril valsartan; vascular remodeling; cardiac vascular ... See more keywords
Cardiac and vascular complications in lupus: Is there a role for sex?
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1098383
Abstract: Systemic lupus erythematosus (SLE) is a common systemic autoimmune disorder and is characterized by autoantibody formation and subsequent immune complex deposition into target organs. SLE affects nearly nine women to every one man worldwide. Patients… read more here.
Keywords: sle; disease; sex; cardiac vascular ... See more keywords
Editorial: Metabolic Regulation of Cardiac and Vascular Cell Function: Physiological and Pathophysiological Implications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.849869
Abstract: Center for Metabolic Disease Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States, Department of Cardiology, Angiology and Pneumology, University Hospital Heidelberg, Heidelberg, Germany, DZHK (German Centre for Cardiovascular Research), Partner Site… read more here.
Keywords: regulation cardiac; editorial metabolic; cardiac vascular; metabolic regulation ... See more keywords
Original research gender differences in recovering from cardiac and vascular surgery associated acute kidney injury: A six-year retrospective comparative study in Nigeria
Sign Up to like & getrecommendations! Published in 2023 at "Annals of African Medicine"
DOI: 10.4103/aam.aam_81_21
Abstract: Introduction: Gender differences exist in the demographic, clinical characteristic and outcome of patients with cardiac and vascular surgery (CVS) associated acute kidney injury (AKI). Materials and Methods: This retrospective study had a total of 88… read more here.
Keywords: vascular surgery; cardiac vascular; kidney; gender differences ... See more keywords