The future of cardiac xenotransplantation
Sign Up to like & getrecommendations! Published in 2022 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-022-00684-y
Abstract: Reflecting on the first genetically engineered pig-to-human heart transplantation in this Clinical Outlook article, we discuss the likely future of cardiac xenotransplantation. Initial clinical trials are expected to explore compassionate use as destination therapy in… read more here.
Keywords: future cardiac; cardiac xenotransplantation; cardiology; heart ... See more keywords
Heart xenotransplantation
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000461
Abstract: Purpose of review Cardiac xenotransplantation has entered an exciting era, marked by numerous considerable advances in the field, and continues to be of great interest because of its potential ability in ameliorating the current constraints… read more here.
Keywords: heart xenotransplantation; xenotransplantation; cardiac xenotransplantation;
Clinical cardiac xenotransplantation first in the clinical arena
Sign Up to like & getrecommendations! Published in 2022 at "Xenotransplantation"
DOI: 10.1111/xen.12734
Abstract: 1 Department of Anaesthesiology, University Hospital, LMUMunich, Munich, Germany 2 Transregional Collaborative Research Center 127,Walter Brendel Centre of ExperimentalMedicine, LMUMunich, Munich, Germany 3 Department of Cardiac Surgery, University Hospital, LMUMunich, Munich, Germany 4 Immunology Research… read more here.
Keywords: clinical cardiac; munich germany; cardiac xenotransplantation; lmumunich munich ... See more keywords
Cardiac Xenotransplantation: Progress in Preclinical Models and Prospects for Clinical Translation
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DOI: 10.3389/ti.2022.10171
Abstract: Survival of pig cardiac xenografts in a non-human primate (NHP) model has improved significantly over the last 4 years with the introduction of costimulation blockade based immunosuppression (IS) and genetically engineered (GE) pig donors. The… read more here.
Keywords: progress preclinical; cardiac xenotransplantation; clinical translation; preclinical models ... See more keywords