Surface-Binding to Cardiolipin Nanodomains Triggers Cytochrome c Pro-apoptotic Peroxidase Activity via Localized Dynamics.
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DOI: 10.1016/j.str.2019.02.007
Abstract: The peroxidation of cardiolipins by reactive oxygen species, which is regulated and enhanced by cytochrome c (cyt c), is a critical signaling event in mitochondrial apoptosis. We probe the molecular underpinnings of this mitochondrial death… read more here.
Keywords: binding cardiolipin; triggers cytochrome; cardiolipin nanodomains; cardiolipin ... See more keywords