Differential and sex- and age-specific risks of cardiometabolic diseases with unrelated metabolic syndrome dimensions.
Sign Up to like & getrecommendations! Published in 2023 at "Obesity"
DOI: 10.1002/oby.23778
Abstract: OBJECTIVE This study aimed to investigate whether independent dimensions of metabolic syndrome (MetS) components are associated differentially with incident cardiometabolic diseases. METHODS Principal components analysis was performed using the five MetS components from 153,073 unrelated… read more here.
Keywords: metabolic syndrome; differential sex; age; sex ... See more keywords
Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-020-05131-6
Abstract: Observational studies have shown a bidirectional association between major depressive disorder (MDD) and cardiometabolic diseases. We conducted a two-sample bidirectional Mendelian randomisation (MR) study to assess the causal associations of MDD with type 2 diabetes,… read more here.
Keywords: cardiometabolic diseases; type diabetes; study; heart failure ... See more keywords
A longitudinal study of rural Bangladeshi children with long-term arsenic and cadmium exposures and biomarkers of cardiometabolic diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.116333
Abstract: There is growing interest in understanding the contribution of environmental toxicant exposure in early life to development of cardiometabolic diseases (CMD) in adulthood. We aimed to assess associations of early life exposure to arsenic and… read more here.
Keywords: study rural; cardiometabolic diseases; childhood associated; cadmium ... See more keywords
Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank.
Sign Up to like & getrecommendations! Published in 2022 at "Nature genetics"
DOI: 10.1038/s41588-021-01011-w
Abstract: Cardiometabolic diseases are the leading cause of death worldwide. Despite a known genetic component, our understanding of these diseases remains incomplete. Here, we analyzed the contribution of rare variants to 57 diseases and 26 cardiometabolic… read more here.
Keywords: underlying cardiometabolic; rare genetic; analysis rare; variation underlying ... See more keywords
Cardiometabolic diseases, frailty, and healthcare utilization and expenditure in community-dwelling Chinese older adults
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-87444-z
Abstract: This study investigated associations between cardiometabolic diseases, frailty, and healthcare utilization and expenditure among Chinese older adults. The participants were 5204 community-dwelling adults aged at least 60 years from the China Health and Retirement Longitudinal… read more here.
Keywords: diseases frailty; cardiometabolic diseases; healthcare utilization; expenditure ... See more keywords
The genetic overlap between mood disorders and cardiometabolic diseases: a systematic review of genome wide and candidate gene studies
Sign Up to like & getrecommendations! Published in 2017 at "Translational Psychiatry"
DOI: 10.1038/tp.2016.261
Abstract: Meta-analyses of genome-wide association studies (meta-GWASs) and candidate gene studies have identified genetic variants associated with cardiovascular diseases, metabolic diseases and mood disorders. Although previous efforts were successful for individual disease conditions (single disease), limited… read more here.
Keywords: genome wide; cardiometabolic diseases; mood disorders; mood ... See more keywords
A systematic review and meta-analysis of dietary interventions modulating gut microbiota and cardiometabolic diseases - striving for new standards in microbiome studies.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.02.011
Abstract: BACKGROUND & AIMS Cardiometabolic diseases (CMD) have shared properties and causes. Insulin resistance is a risk factor and characteristic of CMD and has been suggested to be modulated by gut microbiota (GM) derived plasma metabolites.… read more here.
Keywords: gut microbiota; systematic review; cardiometabolic diseases; dietary interventions ... See more keywords
Fermented food: Should patients with cardiometabolic diseases go back to an early neolithic diet?
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2077300
Abstract: Fermentation has been used since the Early Neolithic period to preserve foods. It has inherent organoleptic and nutritive properties that bestow health benefits, including reducing inflammation and oxidative stress, supporting the growth of salutogenic microbiota,… read more here.
Keywords: food; food patients; patients cardiometabolic; early neolithic ... See more keywords
Frailty and cardiometabolic diseases: a bidirectional Mendelian randomisation study.
Sign Up to like & getrecommendations! Published in 2022 at "Age and ageing"
DOI: 10.1093/ageing/afac256
Abstract: BACKGROUND Frailty is strongly associated with cardiometabolic diseases in observational studies. However, whether the observed association reflects causality requires clarification. We performed a bidirectional Mendelian randomisation (MR) study to assess the causal relationship of frailty,… read more here.
Keywords: randomisation study; mendelian randomisation; frailty; bidirectional mendelian ... See more keywords
5219A novel senolytic drug, seno-7284 ameliorates age-related cardiometabolic diseases
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0068
Abstract: Senescence at cellular level develops with various genotoxic stresses and it plays a pivotal role in aging and age-related disorders. Recently, it was shown that elimination of senescent cells, so called “senolysis” has potential to… read more here.
Keywords: cardiometabolic diseases; mice; seno 7284; age related ... See more keywords
Self-Reported Daytime Napping, Daytime Sleepiness, and Other Sleep Phenotypes in the Development of Cardiometabolic Diseases: A Mendelian Randomization Study.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of preventive cardiology"
DOI: 10.1093/eurjpc/zwac123
Abstract: AIMS Sleep disorders are associated with increased risk of cardiometabolic diseases in observational studies, but the causality remains unclear. In this study, we leveraged two-sample Mendelian randomization (MR) analyses to assess the causal associations of… read more here.
Keywords: daytime sleepiness; daytime napping; self reported; reported daytime ... See more keywords