Protective effect of histone methyltransferase NSD3 on ISO‐induced cardiac hypertrophy
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13515
Abstract: Nuclear receptor‐binding SET domain 3 (NSD3) is a lysine methyltransferase that plays important roles in multiple biological activities; however; its potential roles in the cardiovascular system remain unknown. In this study, we found that NSD3… read more here.
Keywords: cardiomyocyte hypertrophy; protective effect; methyltransferase; hypertrophy ... See more keywords
Shen’ge powder decreases the cardiomyocyte hypertrophy in chronic heart failure by activating the Rho protein/Rho‐associated coiledcoil forming protein kinase signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27386
Abstract: The current study aimed to explore the role and the molecular mechanism of Shen’ge powder in cardiomyocyte hypertrophy in chronic heart failure (CHF). read more here.
Keywords: cardiomyocyte hypertrophy; heart failure; rho; chronic heart ... See more keywords
Sestrin 2 attenuates neonatal rat cardiomyocyte hypertrophy induced by phenylephrine via inhibiting ERK1/2
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3020-2
Abstract: Cardiac hypertrophy is an adaptive response triggered by many physiological and pathological conditions and will lead to heart failure eventually. Sestrin 2, which is a stress-responsive protein, was reported to protect heart from ischemia reperfusion… read more here.
Keywords: hypertrophy induced; cardiomyocyte hypertrophy; induced phenylephrine; hypertrophy ... See more keywords
miR-133a-3p attenuates cardiomyocyte hypertrophy through inhibiting pyroptosis activation by targeting IKKε.
Sign Up to like & getrecommendations! Published in 2020 at "Acta histochemica"
DOI: 10.1016/j.acthis.2020.151653
Abstract: OBJECTIVE Cardiac hypertrophy is an adaptive response to physiological and pathological stimuli, the latter of which frequently progresses to valvulopathy, heart failure and sudden death. Recent reports revealed that pyroptosis is involved in regulating multiple… read more here.
Keywords: cardiac hypertrophy; cardiomyocyte hypertrophy; pyroptosis activation; hypertrophy ... See more keywords
G3bp1 - microRNA-1 axis regulates cardiomyocyte hypertrophy.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2022.110245
Abstract: Adaptation of gene expression is one of the most fundamental response of cardiomyocytes to hypertrophic stimuli. G3bp1, an RNA binding protein with site-specific endoribonuclease activity regulates the processing of pre-miR-1 stem-loop, and thus levels of… read more here.
Keywords: cardiomyocyte hypertrophy; g3bp1; gene expression; hypertrophy ... See more keywords
Carboxypeptidase A4 promotes cardiomyocyte hypertrophy through activating PI3K-AKT-mTOR signaling
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20200669
Abstract: Abstract Carboxypeptidase A4 (CPA4) is a member of the metallocarboxypeptidase family. Current studies have identified the roles of CPA4 in cancer biology and insulin sensitivity. However, the roles of CPA4 in other diseases are not… read more here.
Keywords: hypertrophy; cardiomyocyte hypertrophy; mtor signaling; cpa4 ... See more keywords
P748Afterload-induced TRIF-dependent signaling promotes fibrosis but not cardiomyocyte hypertrophy
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz747.0350
Abstract: Pressure overload dependent cardiac remodeling is characterized by a continuous functional loss of cardiomyocytes, cardiomyocyte hypertrophy, cell death and fibrosis. The relevance of the MyD88- and NFκB-independent inflammatory TRIF (TIR-domain-containing adapter protein inducing IFN-β) signaling… read more here.
Keywords: cardiomyocyte hypertrophy; hypertrophy; trif mice; trif dependent ... See more keywords
Sodium ferulate inhibits rat cardiomyocyte hypertrophy induced by Ang II through enhancement of eNOS/NO/cGMP signaling pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000001277
Abstract: ABSTRACT Sodium ferulate (SF) is the sodium salt of ferulic acid, which is one of the effective components of Angelica sinensis and Lignsticum chuanxiong, and plays an important role in protecting the cardiovascular system. In… read more here.
Keywords: mol; cardiomyocyte hypertrophy; hypertrophy; hypertrophy induced ... See more keywords
The Regulatory Mechanism and Effect of RIPK3 on PE-induced Cardiomyocyte Hypertrophy.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cardiovascular pharmacology"
DOI: 10.1097/fjc.0000000000001293
Abstract: ABSTRACT As a critical regulatory molecule, receptor-interacting protein kinase 3 (RIPK3) can mediate the signaling pathway of programmed necrosis. Calcium/calmodulin-dependent protein kinase II (CaMKII) has been proved as a new substrate for RIPK3-induced necroptosis. In… read more here.
Keywords: cardiomyocyte hypertrophy; hypertrophy; ripk3; ripk3 induced ... See more keywords
Ectopic Acsl6 Overexpression Partially Improves Isoproterenol-Induced Cardiac Hypertrophy In Vivo and Cardiomyocyte Hypertrophy In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001343
Abstract: Supplemental Digital Content is Available in the Text. Abstract: The increase in cardiac myocyte size is a critical issue in cardiac hypertrophy development. In this study, 61 differentially expressed genes between hypertrophic rats and normal… read more here.
Keywords: cardiomyocyte hypertrophy; hypertrophy; iso induced; acsl6 overexpression ... See more keywords
Endothelial Cell-Derived Angiocrines Elicit Physiological Cardiomyocyte Hypertrophy.
Sign Up to like & getrecommendations! Published in 2019 at "Circulation"
DOI: 10.1161/circulationaha.119.040632
Abstract: Cardiac growth is a major adaptive response to elevated workload on the heart, one that facilitates a decrease in ventricular wall stress and helps sustain pump function.1 Because most mammalian cardiomyocytes become terminally differentiated and… read more here.
Keywords: hypertrophy; growth; cardiomyocyte hypertrophy; heart ... See more keywords