AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury.
Sign Up to like & getrecommendations! Published in 2021 at "Biomedical journal"
DOI: 10.1016/j.bj.2021.11.012
Abstract: BACKGROUND Hypoxia-induced apoptosis is linked to the pathogenesis of myocardial infarction. The role of apoptosis-inducing factor mitochondria associated 1 (AIFM1) in cardiomyocyte injury remains unclear. This study was aimed at probing into the role and… read more here.
Keywords: expression; hypoxia induced; injury; mir 145 ... See more keywords
MiR-208a aggravates H2O2-induced cardiomyocyte injury by targeting APC.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172668
Abstract: Oxidative stress injury, inducing cardiomyocyte injury, is the major denominator of many cardiovascular diseases. In present study, we aimed to explore the molecular mechanism of microRNA-208a (miR-208a) in oxidative stress-induced cardiomyocyte injury. In this study,… read more here.
Keywords: mir 208a; apc; cardiomyocyte injury; h2o2 induced ... See more keywords
MicroRNA miR-215-5p Regulates Doxorubicin-induced Cardiomyocyte Injury by Targeting ZEB2
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001110
Abstract: Abstract: Doxorubicin (DOX) is a chemotherapeutic drug for treating various cancers. However, the DOX-induced cardiotoxicity greatly limits its clinical application. MicroRNAs are emerged as critical mediators of cardiomyocyte injury. This work explored the function of… read more here.
Keywords: mir 215; dox induced; induced cardiomyocyte; injury ... See more keywords
miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology Research and Practice"
DOI: 10.1155/2022/7687154
Abstract: Sepsis is a systemic inflammation and is capable of inducing myocarditis, which is a major leading cause of death in patients. Studies have found that miR-197 is correlated with the prognosis of patients with inflammatory… read more here.
Keywords: h9c2 cells; cardiomyocyte injury; mir 197; induced cardiomyocyte ... See more keywords
Knockdown of long non-coding RNA LUCAT1 reverses high glucose-induced cardiomyocyte injury via targeting CYP11B2.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201910_19171
Abstract: OBJECTIVE Diabetic cardiomyopathy (DCM) is one of the major complications in patients with diabetes mellitus. Recently, long noncoding RNAs (lncRNAs) have been well concerned for their roles in the progression of multiple diseases, including DCM.… read more here.
Keywords: high glucose; cardiomyocyte injury; induced cardiomyocyte; lucat1 ... See more keywords
Mitofusin 2 Participates in Mitophagy and Mitochondrial Fusion Against Angiotensin II-Induced Cardiomyocyte Injury
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00411
Abstract: Background Mitochondrial dynamics play a critical role in mitochondrial function. The mitofusin 2 (MFN2) gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion to maintain and operate the mitochondrial network. Moreover, MFN2 is… read more here.
Keywords: microscopy; cardiomyocyte injury; mitochondrial fusion; ang ... See more keywords
Inhibition of TLR4 Alleviates Heat Stroke-Induced Cardiomyocyte Injury by Down-Regulating Inflammation and Ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28052297
Abstract: Inflammatory response and cell death play key roles in the mechanism of myocardial cell injury induced by heat stroke (HS) in rats. Ferroptosis is a newly discovered regulatory type of cell death, which is involved… read more here.
Keywords: h9c2 cells; heat stroke; tlr4; ferroptosis ... See more keywords
Curcumin attenuates hypoxia/reoxygenation-induced cardiomyocyte injury by downregulating Notch signaling
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2019.10371
Abstract: Recovery of the blood supply is the most effective treatment against ischemic heart disease; however, it is also a major cause of myocardial ischemia/reperfusion injury in clinical therapy. Curcumin has been reported to possess beneficial… read more here.
Keywords: hypoxia reoxygenation; reoxygenation induced; cardiomyocyte injury; induced cardiomyocyte ... See more keywords
Positive feedback loop of lncRNA SNHG1/miR‑16‑5p/GATA4 in the regulation of hypoxia/reoxygenation‑induced cardiomyocyte injury.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular medicine reports"
DOI: 10.3892/mmr.2021.12544
Abstract: Numerous studies have demonstrated that long non‑coding RNAs (lncRNAs) serve an important regulatory role in ischemic injury of cardiomyocytes. lncRNA small nucleolar RNA host gene 1 (SNHG1) could effectively protect cardiomyocytes against various injuries. However,… read more here.
Keywords: snhg1; cardiomyocyte injury; snhg1 mir; gata4 ... See more keywords