Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence
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DOI: 10.1016/j.ebiom.2018.11.056
Abstract: Background Cellular senescence is a stable cell-cycle arrest induced by telomere shortening and various types of cellular stress including oxidative stress, oncogene activation, DNA damage etc. Heme oxygenase-1 (HO-1) is an inducible stress-response protein that… read more here.
Keywords: cardiomyocyte senescence; heart; heart function; senescence ... See more keywords
Protocatechuic Aldehyde Alleviates d-Galactose–Induced Cardiomyocyte Senescence by Regulating the TCF3/ATG5 Axis
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DOI: 10.1097/fjc.0000000000001394
Abstract: Abstract: Cardiomyocyte senescence is an independent risk factor for cardiovascular diseases. Protocatechuic aldehyde (PCA) is a natural chemical in the Chinese medicinal herb Salvia miltiorrhiza. PCA could protect against oxidative stress and inflammation in the… read more here.
Keywords: inflammation; atg5; galactose induced; cardiomyocyte senescence ... See more keywords
Atrial Fibrillation Underlies Cardiomyocyte Senescence and Contributes to Deleterious Atrial Remodeling during Disease Progression
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DOI: 10.14336/ad.2021.0619
Abstract: Accelerated senescence is triggered by key mediators of arrhythmogenic substrates and contributes to atrial fibrillation (AF). We sought to understand senescence in AF and the extent to which it aggravates the AF process. Twenty-six AF… read more here.
Keywords: senescence contributes; contributes deleterious; cardiomyocyte senescence; underlies cardiomyocyte ... See more keywords