sox9b is required in cardiomyocytes for cardiac morphogenesis and function
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32125-7
Abstract: The high mobility group transcription factor SOX9 is expressed in stem cells, progenitor cells, and differentiated cell-types in developing and mature organs. Exposure to a variety of toxicants including dioxin, di(2-ethylhexyl) phthalate, 6:2 chlorinated polyfluorinated… read more here.
Keywords: sox9b function; sox9b; function; development ... See more keywords
Cardiomyocyte-specific deletion of β-catenin protects mouse hearts from ventricular arrhythmias after myocardial infarction
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DOI: 10.1038/s41598-021-97176-9
Abstract: Wnt/β-catenin signaling is activated in the heart after myocardial infarction (MI). This study aims to investigate if β-catenin deletion affects post-MI ion channel gene alterations and ventricular tachycardias (VT). MI was induced by permanent ligation… read more here.
Keywords: channel gene; myocardial infarction; catenin; deletion ... See more keywords
Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007674
Abstract: Viral myocarditis is a serious disease, commonly caused by type B coxsackieviruses (CVB). Here we show that innate immune protection against CVB3 myocarditis requires the IFIT (IFN-induced with tetratricopeptide) locus, which acts in a biphasic… read more here.
Keywords: infection; ifit; biphasic cardiomyocyte; replication ... See more keywords