Epigenetic and metabolic alterations in human amniotic fluid stem cells induced to cardiomyogenic differentiation by DNA methyltransferases and p53 inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28092
Abstract: Human amniotic fluid‐derived mesenchymal stem cells (AF‐MSCs) may be a valuable source for cell therapy and regenerative medicine. In this study, the potential of DNA methyltransferases (DNMT) inhibitors Decitabine, Zebularine, RG108 alone or combined with… read more here.
Keywords: cardiomyogenic differentiation; dna methyltransferases; differentiation; human amniotic ... See more keywords
Mechanical stretch promotes antioxidant responses and cardiomyogenic differentiation in P19 cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3184
Abstract: Accumulating evidence has suggested that mechanical stimuli play a crucial role in regulating the lineage‐specific differentiation of stem cells through fine‐tuning redox balance. We aimed to investigate the effects of cyclic tensile strain (CTS) on… read more here.
Keywords: cardiomyogenic differentiation; differentiation p19; differentiation; expression antioxidant ... See more keywords