Clinical characteristics and determinants of phenotype in TMEM43 Arrhythmogenic right ventricular cardiomyopathy type 5.
Sign Up to like & getrecommendations! Published in 2020 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2020.01.035
Abstract: BACKGROUND Arrhythmogenic right ventricular cardiomyopathy type V (ARVC-5) is the most aggressive heterozygous form of ARVC. It is predominantly caused by a fully penetrant mutation (p.S358L) in the non-desmosomal gene TMEM43 - endemic to Newfoundland,… read more here.
Keywords: ventricular cardiomyopathy; phenotype tmem43; right ventricular; background ... See more keywords
Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling
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DOI: 10.1038/s42003-021-02291-y
Abstract: Patients with long-standing diabetes have a high risk for cardiac complications that is exacerbated by increased reactive oxygen species (ROS) production. We found that feeding cyanocobalamin (B12), a scavenger of superoxide, not only prevented but… read more here.
Keywords: dnmt socs1; cardiomyopathy type; igf; dnmt ... See more keywords