Cardioprotective effect of thyroid hormone is mediated by AT2 receptor and involves nitric oxide production via Akt activation in mice
Sign Up to like & getrecommendations! Published in 2017 at "Heart and Vessels"
DOI: 10.1007/s00380-017-1101-5
Abstract: Studies have demonstrated that thyroid hormone (T3) can precondition the heart against ischaemic injury and improve post-ischaemic recovery. This study investigated whether the AT2 receptor (AT2R) is involved in cardioprotection and the potential molecular mechanism… read more here.
Keywords: at2 receptor; production; effect; mice ... See more keywords
Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-67247-4
Abstract: Ischemia reperfusion (IR) injury may be attenuated through succinate dehydrogenase (SDH) inhibition by dimethyl malonate (DiMAL). Whether SDH inhibition yields protection in diabetic individuals and translates into human cardiac tissue remain unknown. In isolated perfused… read more here.
Keywords: cardioprotective effect; without diabetes; inhibition; succinate dehydrogenase ... See more keywords
Cardioprotective effect of combination therapy by mild hypothermia and local or remote ischemic preconditioning in isolated rat hearts
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DOI: 10.1038/s41598-020-79449-x
Abstract: A multitargeted strategy to treat the consequences of ischemia and reperfusion (IR) injury in acute myocardial infarction may add cardioprotection beyond reperfusion therapy alone. We investigated the cardioprotective effect of mild hypothermia combined with local… read more here.
Keywords: hypothermia; mild hypothermia; ischemic preconditioning; cardioprotective effect ... See more keywords
CARDIOPROTECTIVE EFFECT OF MORIN AGAINST OXIDATIVE STRESS AND APOPTOTIC DAMAGE IN EXPERIMENTAL MODEL OF ISOPROTERENOL INDUCED MYOCARDIAL NECROSIS IN RATS
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000571308.93127.cc
Abstract: Objective:Myocardial infarction continues to be associated with high morbidity and mortality worldwide despite the availability of current therapeutic modalities. Morin, a bioflavonoid has known to possess good antioxidant, immunomodulatory and anti-apoptotic properties in previous studies.… read more here.
Keywords: apoptotic damage; morin oxidative; cardioprotective effect; stress apoptotic ... See more keywords
The cardioprotective effect of astaxanthin against isoprenaline-induced myocardial injury in rats: involvement of TLR4/NF-κB signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202106_26052
Abstract: OBJECTIVE Cardiovascular diseases (CVDs) are a major cause of morbidity and mortality around the world. Nuclear transcription factor kappa B (NF-κB) represents a factor that plays a major role in the pathogenesis of CVDs. The… read more here.
Keywords: cardioprotective effect; induced myocardial; myocardial injury; isoprenaline induced ... See more keywords
Cardioprotective Effect of Low Level of LDL Cholesterol on Perioperative Myocardial Injury in Off-Pump Coronary Artery Bypass Grafting
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DOI: 10.3390/medicina57090875
Abstract: Background and Objectives: Coronary artery disease is still a major cause of death in developed countries. Low-density lipoprotein cholesterol (LDL-C) lowering with statin therapy is a key strategy in major acute coronary events’ prevention. The… read more here.
Keywords: ldl; cholesterol; coronary artery; pump coronary ... See more keywords
Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation
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DOI: 10.3390/nu14132742
Abstract: Earlier studies reported that long-term treatment with thymoquinone (TQ) at a high dose (20 mg/kg) exerts a cardioprotective effect against isoproterenol (ISO)-triggered myocardial infarction (MI) in rats. In the present study, we tested the hypothesis… read more here.
Keywords: produces cardioprotective; thymoquinone; cardioprotective effect; effect receptor ... See more keywords
Cardioprotective Effect of Flibanserin against Isoproterenol-Induced Myocardial Infarction in Female Rats: Role of Cardiac 5-HT2A Receptor Gene/5-HT/Ca2+ Pathway
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040502
Abstract: Myocardial infarction (MI) is a life-threatening ischemic disease and is one of the leading causes of morbidity and mortality worldwide. Serotonin (5-HT) release during myocardial ischemia plays an important role in the progression of myocardial… read more here.
Keywords: myocardial infarction; induced myocardial; cardioprotective effect; iso induced ... See more keywords