Cardiotoxic Effects of Antibody Drug Conjugates vs Standard Chemotherapy in ERBB2-Positive Advanced Breast Cancer
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.40336
Abstract: Key Points Question What is the incidence of cardiotoxic effects of novel antibody-drug conjugates compared with the standard-of-care chemotherapy regimens containing trastuzumab for ERBB2-positive locally advanced or metastatic breast cancer? Findings In this systematic review… read more here.
Keywords: cardiotoxic effects; decrease trastuzumab; chemotherapy; lvef decrease ... See more keywords
Assessment of late cardiotoxic effects in patients treated for cancer in childhood
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4564
Abstract: The most frequent chemotherapeutic regimens used in children's cancer contain anthracyclines, which may have potentially cardiotoxic effects even at a later point in time. Echocardiography including tissue Doppler imaging is well‐proved noninvasive method to assess… read more here.
Keywords: late cardiotoxic; assessment late; cardiotoxic effects; patients treated ... See more keywords
Perfluorononanoate and Perfluorobutane Sulfonate Induce Cardiotoxic Effects in Zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5447
Abstract: Globally, per‐ and polyfluoroalkyl substances are common artificial ingredients in industrial and consumer products. Recently, they have been shown to be an emerging human health risk. Perfluorononanoic acid (PFNA)/perfluorononanoate and perfluorobutane sulfonic acid (PFBS)/perfluorobutane sulfonate… read more here.
Keywords: toxicology; pfbs; cardiotoxic effects; chemistry ... See more keywords
Cardiotoxic Effects of Micrurus surinamensis (Cuvier, 1817) Snake Venom.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular toxicology"
DOI: 10.1007/s12012-021-09640-7
Abstract: Micrurus surinamensis is a coral snake from the Elapidae family of wide distribution in Amazonia Forest. Its venom contains neurotoxins that induce muscular and respiratory paralysis; however, its cardiovascular action is not yet characterized. The… read more here.
Keywords: venom; micrurus surinamensis; snake; cardiotoxic effects ... See more keywords
A systematic review of long-term cardiotoxic effects of treatment in survivors of childhood acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2025 at "Molecular and Cellular Pediatrics"
DOI: 10.1186/s40348-025-00196-y
Abstract: As progress in medical interventions for childhood cancer advances, the number of survivors of childhood acute lymphoblastic leukemia (ALL) is rising. Presently, the overall survival rate exceeds 90% over a five-year period. With this upward… read more here.
Keywords: term cardiotoxic; cardiotoxic effects; long term; survivors childhood ... See more keywords
Toxicology of Trastuzumab: An Insight into Mechanisms of Cardiotoxicity.
Sign Up to like & getrecommendations! Published in 2019 at "Current cancer drug targets"
DOI: 10.2174/1568009618666171129222159
Abstract: Trastuzumab is a humanized monoclonal antibody that is approved for the treatment of breast and gastric malignancies. Although it has shown promise as a biotherapeutic, its cardiotoxicity remains a major concern. Genotoxic anticancer anthracyclines such… read more here.
Keywords: trastuzumab; toxicology trastuzumab; cardiotoxicity; cardiotoxic effects ... See more keywords
Changes in the Cardiotoxic Effects of Lead Intoxication in Rats Induced by Muscular Exercise
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23084417
Abstract: Exposure to lead is associated with an increased risk of cardiovascular diseases. Outbred white male rats were injected with lead acetate intraperitoneally three times a week and/or were forced to run at a speed of… read more here.
Keywords: cardiotoxic effects; changes cardiotoxic; intoxication; lead intoxication ... See more keywords