Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study
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DOI: 10.1097/md.0000000000030000
Abstract: To assess the clinical effect of astragalus polysaccharide in preventing cardiotoxicity induced by chemotherapy of epirubicin. Two hundred forty-eight patients with breast cancer or malignant lymphoma were randomly divided into the experimental group (EG) (n… read more here.
Keywords: chemotherapy epirubicin; astragalus polysaccharide; epirubicin; cardiotoxicity ... See more keywords
Schisandrin B Antagonizes Cardiotoxicity Induced by Pirarubicin by Inhibiting Mitochondrial Permeability Transition Pore (mPTP) Opening and Decreasing Cardiomyocyte Apoptosis
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DOI: 10.3389/fphar.2021.733805
Abstract: Objective: Pirarubicin (THP), one of the anthracycline anticancer drugs, is widely used in the treatment of various cancers, but its cardiotoxicity cannot be ignored. Schisandrin B (SchB) has the ability to upregulate cellular antioxidant defense… read more here.
Keywords: thp; mptp opening; apoptosis; cardiotoxicity induced ... See more keywords
Characteristics and Spectrum of Cardiotoxicity Induced by Various Antipsychotics: A Real-World Study From 2015 to 2020 Based on FAERS
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DOI: 10.3389/fphar.2021.815151
Abstract: Objective: This study aimed to investigate the characteristics and spectrum of cardiotoxicity induced by various antipsychotics based on the United States Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database. Methods: Data of… read more here.
Keywords: induced various; cardiotoxicity induced; various antipsychotics; spectrum cardiotoxicity ... See more keywords
Cardiotoxicity Induced by Protein Kinase Inhibitors in Patients with Cancer
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DOI: 10.3390/ijms23052815
Abstract: Kinase inhibitors (KIs) represent a growing class of drugs directed at various protein kinases and used in the treatment of both solid tumors and hematologic malignancies. It is a heterogeneous group of compounds that are… read more here.
Keywords: protein kinase; cardiotoxicity induced; kinase inhibitors; kinase ... See more keywords