Streptozotocin-induced hyperglycemia unmasks cardiotoxicity induced by doxorubicin
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DOI: 10.1038/s41598-025-91824-0
Abstract: Late-onset cardiotoxicity induced by anthracyclines occurs years to decades after completion of anti-cancer therapy and is associated with increased morbi-mortality of cancer survivors. Chemotherapy at the time of treatment probably causes cardiac damages for which… read more here.
Keywords: induced hyperglycemia; dox stz; dox; cardiotoxicity induced ... See more keywords
Cardiotoxicity induced by xanthatin via activating apoptosis and ERS pathways in zebrafish
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DOI: 10.1080/01480545.2025.2481863
Abstract: Abstract Xanthatin, a sesquiterpene lactone compound, isolated from Chinese herb, Xanthium strumarium L, has various activities, including anti-inflammatory, anti-tumor, anti-ulcer effects. However, it has been less studied in terms of its toxicity, especially the potential… read more here.
Keywords: xanthatin; cardiotoxicity induced; cardiotoxicity; induced xanthatin ... See more keywords
Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030000
Abstract: To assess the clinical effect of astragalus polysaccharide in preventing cardiotoxicity induced by chemotherapy of epirubicin. Two hundred forty-eight patients with breast cancer or malignant lymphoma were randomly divided into the experimental group (EG) (n… read more here.
Keywords: chemotherapy epirubicin; astragalus polysaccharide; epirubicin; cardiotoxicity ... See more keywords
Cardioprotective Efficacy of Quercetin against Cardiotoxicity Induced by Different Diameters of Sphere Gold Nanoparticles (GNPs).
Sign Up to like & getrecommendations! Published in 2024 at "Current pharmaceutical biotechnology"
DOI: 10.2174/0113892010359481241122073753
Abstract: BACKGROUND Gold nanoparticles (GNPs) have garnered significant attention in the biomedicine field due to their exceptional electrical, mechanical, chemical, and optical characteristics. The interaction of these remarkable potentials with biological tissues carries a risk of… read more here.
Keywords: cardiotoxicity induced; induced different; cardiotoxicity; nanoparticles gnps ... See more keywords
Schisandrin B Antagonizes Cardiotoxicity Induced by Pirarubicin by Inhibiting Mitochondrial Permeability Transition Pore (mPTP) Opening and Decreasing Cardiomyocyte Apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.733805
Abstract: Objective: Pirarubicin (THP), one of the anthracycline anticancer drugs, is widely used in the treatment of various cancers, but its cardiotoxicity cannot be ignored. Schisandrin B (SchB) has the ability to upregulate cellular antioxidant defense… read more here.
Keywords: thp; mptp opening; apoptosis; cardiotoxicity induced ... See more keywords
Characteristics and Spectrum of Cardiotoxicity Induced by Various Antipsychotics: A Real-World Study From 2015 to 2020 Based on FAERS
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.815151
Abstract: Objective: This study aimed to investigate the characteristics and spectrum of cardiotoxicity induced by various antipsychotics based on the United States Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) database. Methods: Data of… read more here.
Keywords: induced various; cardiotoxicity induced; various antipsychotics; spectrum cardiotoxicity ... See more keywords
Cardiotoxicity Induced by Protein Kinase Inhibitors in Patients with Cancer
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DOI: 10.3390/ijms23052815
Abstract: Kinase inhibitors (KIs) represent a growing class of drugs directed at various protein kinases and used in the treatment of both solid tumors and hematologic malignancies. It is a heterogeneous group of compounds that are… read more here.
Keywords: protein kinase; cardiotoxicity induced; kinase inhibitors; kinase ... See more keywords
Cardiotoxicity Induced by Anticancer Therapies: A Call for Integrated Cardio-Oncology Practice
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DOI: 10.3390/ph18091399
Abstract: The introduction of novel oncologic therapies, including targeted agents, immunotherapies, and antibody–drug conjugates, has transformed the therapeutic landscape of cancer care. This evolution has resulted in a dual clinical scenario; while survival outcomes have markedly… read more here.
Keywords: oncology; cardiotoxicity induced; cardiotoxicity; induced anticancer ... See more keywords