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Published in 2023 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23644
Abstract: Photobiomodulation (PBM) therapy, a form of low‐dose light therapy, has been noted to be effective in several age‐associated chronic diseases such as hypertension and atherosclerosis. Here, we examined the effects of PBM therapy on age‐associated…
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Keywords:
photobiomodulation therapy;
mitigates cardiovascular;
therapy;
cardiovascular aging ... See more keywords
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Published in 2025 at "GeroScience"
DOI: 10.1007/s11357-025-01613-w
Abstract: The pathology of cardiovascular aging is complex, involving mitochondrial dysfunction, oxidative and nitrative stress, oxidative DNA injury, impaired lipid metabolism, cell death, senescence, and chronic inflammation. These processes lead to remodeling and structural changes in…
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Keywords:
cardiovascular aging;
alcohol consumption;
alcohol;
reserve capacity ... See more keywords
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Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2019.06.053
Abstract: Heart failure (HF) is a clinical syndrome that usually develops in the elderly. Complex interactions of the cardiovascular aging process with risk factors (obesity, hypertension, and atherosclerosis), comorbidities (anemia, chronic kidney disease, diabetes, and so…
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Keywords:
aging heart;
review;
heart failure;
cardiovascular aging ... See more keywords
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Published in 2025 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvaf138
Abstract: Abstract Most acquired cardiovascular diseases are more common in older people, and the biological mechanisms and manifestations of aging provide insight into cardiovascular pathophysiology. Measuring aging within the cardiovascular system may help to better understand…
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Keywords:
cardiovascular aging;
model cardiovascular;
measure model;
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Published in 2024 at "Aging and Disease"
DOI: 10.14336/ad.2024.0058
Abstract: Cardiovascular aging is a progressive remodeling process constituting a variety of cellular and molecular alterations that are closely linked to mitochondrial dysfunction. Therefore, gaining a deeper understanding of the changes in mitochondrial function during cardiovascular…
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Keywords:
understanding tackling;
cardiovascular aging;
dysfunction roadmap;
mitochondrial dysfunction ... See more keywords
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Published in 2025 at "Aging and disease"
DOI: 10.14336/ad.2025.0272
Abstract: Spatial omics provides unprecedented insights into how the cardiovascular system is spatially organized and how cellular phenotypes are distributed. Researchers have been able to clarify the complex spatial architecture of the cardiovascular system and how…
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Keywords:
spatial omics;
cardiovascular system;
insights cardiovascular;
cardiovascular aging ... See more keywords
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Published in 2024 at "Clinical Interventions in Aging"
DOI: 10.2147/cia.s457180
Abstract: Abstract The aim of this manuscript is to provide a review of available options to enhance cardiovascular health and prevent cardiovascular disease (CVD) in the aging population using a systems-biology approach. These include the role…
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Keywords:
addressing missing;
cardiovascular aging;
missing links;
aging addressing ... See more keywords
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Published in 2024 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2024.1384996
Abstract: Aging leads to physiological changes, including inflammaging—a chronic low-grade inflammatory state with significant implications for various physiological systems, particularly for cardiovascular health. Concurrently, immunosenescence—the age-related decline in immune function, exacerbates vulnerabilities to cardiovascular pathologies in…
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Keywords:
inflammaging immunosenescence;
immunosenescence;
cardiovascular aging;
immunosenescence cardiovascular ... See more keywords
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Published in 2017 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2017.01035
Abstract: Apelin is the endogenous ligand of APJ, the orphan G protein-coupled receptor. The apelin–APJ signal transduction pathway is widely expressed in the cardiovascular system and is an important factor in cardiovascular homeostasis. This signal transduction…
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Keywords:
transduction pathway;
effects apelin;
signal transduction;
apelin cardiovascular ... See more keywords
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Published in 2025 at "Applied Sciences"
DOI: 10.3390/app15095077
Abstract: Background: The aging population is increasing rapidly, with individuals aged 65 and older now representing more than 15% of the global population. This demographic shift is associated with a rising incidence of age-related cardiovascular diseases…
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Keywords:
integration;
predicting cardiovascular;
risk;
individuals aged ... See more keywords
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Published in 2025 at "Diagnostics"
DOI: 10.3390/diagnostics15151903
Abstract: Background: This study presents an innovative approach to cardiovascular disease (CVD) risk prediction based on a comprehensive analysis of clinical, immunological and biochemical markers using mathematical modelling and machine learning methods. Baseline data include indices…
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Keywords:
multimodal computational;
clinical biochemical;
cardiovascular aging;
computational approach ... See more keywords