Ischemic Microenvironment-Responsive Therapeutics for Cardiovascular Diseases.
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DOI: 10.1002/adma.202105348
Abstract: Cardiovascular diseases caused by ischemia are attracting considerable attention owing to its high morbidity and mortality worldwide. Although numerous agents with cardioprotective benefits have been identified, their clinical outcomes are hampered by their low bioavailability,… read more here.
Keywords: ischemic microenvironment; microenvironment responsive; responsive therapeutics; cardiovascular diseases ... See more keywords
Development of Innovative Biomaterials and Devices for the Treatment of Cardiovascular Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202201971
Abstract: Cardiovascular diseases have become the leading cause of death worldwide. The increasing burden of cardiovascular diseases has become a major public health problem and how to carry out efficient and reliable treatment of cardiovascular diseases… read more here.
Keywords: treatment cardiovascular; cardiovascular diseases; innovative biomaterials; biomaterials devices ... See more keywords
Colchicine, a microtubule‐disassembling drug, in the therapy of cardiovascular diseases
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biology International"
DOI: 10.1002/cbin.10988
Abstract: Colchicum autumnale, from which colchicine has been isolated more than 100 years ago, has been used as a treatment for pain and swelling for thousands of years. It is one of the few drugs known… read more here.
Keywords: drug; colchicine; therapy cardiovascular; cardiovascular diseases ... See more keywords
Emerging role of m6 A modification in cardiovascular diseases.
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DOI: 10.1002/cbin.11773
Abstract: Cardiovascular diseases (CVDs) contribute to the leading cause of death worldwide. Despite significantly improvements in CVDs diagnosis and treatment, a continued effort to explore novel therapeutic strategies is urgently need. N6-methyladenosine (m6 A) RNA methylation,… read more here.
Keywords: modification cardiovascular; role modification; cardiovascular diseases; role ... See more keywords
Associations of siesta and total sleep duration with hypertension or cardiovascular diseases in middle‐aged and older adults
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DOI: 10.1002/clc.23954
Abstract: Whether the ratio of siesta duration in the total sleep duration was associated with the occurrence of hypertension or cardiovascular diseases (CVDs) was unclear. read more here.
Keywords: cardiovascular diseases; total sleep; sleep duration; duration ... See more keywords
Use of Mendelian randomization to evaluate the effect of atrial fibrillation on cardiovascular diseases and cardiac death
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DOI: 10.1002/ehf2.14237
Abstract: Several observational studies indicated that atrial fibrillation might aggravate other cardiovascular diseases apart from ischaemic stroke. However, it remains to be determined whether these associations reveal independent causation. Using Mendelian randomization (MR), we systematically investigated… read more here.
Keywords: mendelian randomization; cardiovascular diseases; cardiac death; diseases cardiac ... See more keywords
Autonomic and respiratory consequences of altered chemoreflex function: clinical and therapeutic implications in cardiovascular diseases.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of heart failure"
DOI: 10.1002/ejhf.2819
Abstract: The importance of chemoreflex function for cardiovascular health is increasingly recognized in clinical practice. The physiological function of the chemoreflex is to constantly adjust ventilation and circulatory control to match respiratory gases to metabolism. This… read more here.
Keywords: function; respiratory consequences; chemoreflex function; cardiovascular diseases ... See more keywords
CardioVAI: An automatic implementation of ACMG‐AMP variant interpretation guidelines in the diagnosis of cardiovascular diseases
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DOI: 10.1002/humu.23665
Abstract: Variant interpretation for the diagnosis of genetic diseases is a complex process. The American College of Medical Genetics and Genomics, with the Association for Molecular Pathology, have proposed a set of evidence‐based guidelines to support… read more here.
Keywords: interpretation; diagnosis; implementation; cardiovai ... See more keywords
Gene therapy in cardiovascular diseases: A review of recent updates
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DOI: 10.1002/jcb.27303
Abstract: Gene therapy is considered as a promising approach for treating cardiac dysfunction. In this review, we evaluated the clinical trials assessing gene therapy in cardiovascular diseases (CVD) from 2000 to 2017. PubMed and ClinicalTrials.gov (only… read more here.
Keywords: gene therapy; therapy cardiovascular; cardiovascular diseases; clinical trials ... See more keywords
Prediction for cardiovascular diseases based on laboratory data: An analysis of random forest model
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DOI: 10.1002/jcla.23421
Abstract: To establish a prediction model for cardiovascular diseases (CVD) in the general population based on random forests. read more here.
Keywords: analysis; prediction cardiovascular; cardiovascular diseases; model ... See more keywords
Therapeutic potential of A2 adenosine receptor pharmacological regulators in the treatment of cardiovascular diseases, recent progress, and prospective
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27161
Abstract: Adenosine and its analogs are of particular interest as potential therapeutic agents for treatment of cardiovascular diseases (CVDs). A2 adenosine receptor subtypes (A2a and A2b) are extensively expressed in cardiovascular system, and modulation of these… read more here.
Keywords: adenosine receptor; pharmacological regulators; cardiovascular diseases; treatment cardiovascular ... See more keywords