Sub-therapeutic doses of fluvastatin and valsartan are more effective than therapeutic doses in providing beneficial cardiovascular pleiotropic effects in rats: A proof of concept study.
Sign Up to like & getrecommendations! Published in 2017 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2017.09.005
Abstract: BACKGROUND Statins and sartans can, in therapeutic doses, induce pleiotropic cardiovascular effects. Similar has recently been shown also for sub-therapeutic doses. We thus explored and compared the cardiovascular pleiotropic efficacy of sub-therapeutic vs. therapeutic doses.… read more here.
Keywords: sub therapeutic; therapeutic doses; doses fluvastatin; fluvastatin valsartan ... See more keywords
Cardiovascular Pleiotropic Effects of Natriuretic Peptides
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20163874
Abstract: Atrial natriuretic peptide (ANP) is a cardiac hormone belonging to the family of natriuretic peptides (NPs). ANP exerts diuretic, natriuretic, and vasodilatory effects that contribute to maintain water–salt balance and regulate blood pressure. Besides these… read more here.
Keywords: cardiovascular pleiotropic; natriuretic peptide; natriuretic peptides; pleiotropic effects ... See more keywords