Articles with "cardiovascular safety" as a keyword



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Cardiovascular safety of phosphodiesterase inhibitors for treating erectile dysfunction in elderly men

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Published in 2017 at "Cochrane Database of Systematic Reviews"

DOI: 10.1002/14651858.cd011178.pub2

Abstract: Reason for withdrawal from publication This protocol has been withdrawn as the author team is unable to progress to the final review stage. This title is not open to a new author team as it… read more here.

Keywords: treating erectile; inhibitors treating; erectile dysfunction; cardiovascular safety ... See more keywords

Cardiovascular Safety of VIAN‐c4551, an Antiangiogenic Peptide Derived From Vasoinhibin

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Published in 2025 at "Drug Development Research"

DOI: 10.1002/ddr.70177

Abstract: Vasoinhibin is a potent antiangiogenic protein that blocks the activation of endothelial nitric oxide synthase (eNOS) in response to vascular endothelial growth factor, bradykinin, and acetylcholine (ACh). In this regard, VIAN‐c4551, a new synthetic vasoinhibin… read more here.

Keywords: c4551; peptide; cardiovascular safety; vian c4551 ... See more keywords
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Cardiovascular Safety of Denosumab Across Multiple Indications: A Systematic Review and Meta‐Analysis of Randomized Trials

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Published in 2020 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4157

Abstract: The cardiovascular safety of denosumab has not yet been evaluated in a systematic review. This systematic review and meta‐analysis sought to quantify the number of randomized controlled trials (RCTs) of denosumab (against comparators) reporting cardiovascular… read more here.

Keywords: analysis; systematic review; cardiovascular safety; versus ... See more keywords

Cardiovascular Safety of Antidiabetic Drugs in the Hospital Setting

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Published in 2017 at "Current Diabetes Reports"

DOI: 10.1007/s11892-017-0884-1

Abstract: Purpose of ReviewPatients with diabetes and/or stress hyperglycemia requires good glycemic control in the hospital setting, often requiring the use of glucose-lowering therapy. Standard-of-care dictates that non-insulin therapy be discontinued, with insulin therapy initiated using… read more here.

Keywords: antidiabetic drugs; safety; insulin therapy; cardiovascular safety ... See more keywords

Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs

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Published in 2020 at "Drugs"

DOI: 10.1007/s40265-020-01364-2

Abstract: The incidence of osteoporosis and cardiovascular disease increases with age, and there are potentially shared mechanistic associations between the two conditions. It is therefore highly relevant to understand the cardiovascular implications of osteoporosis medications. These… read more here.

Keywords: anti osteoporosis; assessment cardiovascular; safety anti; cardiovascular safety ... See more keywords
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Cardiovascular Outcome Trials of Diabetes and Obesity Drugs: Implications for Conditional Approval and Early Phase Clinical Development

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Published in 2017 at "Pharmaceutical Medicine"

DOI: 10.1007/s40290-017-0209-3

Abstract: Over the past decade, clinical development and regulatory review of investigational drugs for diabetes and obesity have been guided by heightened standards for pre- and post-marketing assessment of cardiovascular safety. In high-risk patients with type… read more here.

Keywords: risk; diabetes obesity; clinical development; cardiovascular safety ... See more keywords

A comprehensive review of the FDA-approved labels of diabetes drugs: Indications, safety, and emerging cardiovascular safety data.

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Published in 2017 at "Journal of diabetes and its complications"

DOI: 10.1016/j.jdiacomp.2017.08.005

Abstract: AIMS FDA-approved drug labels are an important source of information for clinicians who prescribe medications for treatment of diabetes. We reviewed drug labels to (1) understand the landscape of classes of medications approved for type… read more here.

Keywords: drug labels; safety; cardiovascular safety; fda approved ... See more keywords

Cardiovascular safety of liraglutide for the treatment of type 2 diabetes

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Published in 2017 at "Expert Opinion on Drug Safety"

DOI: 10.1080/14740338.2017.1313225

Abstract: ABSTRACT Introduction: Liraglutide is a GLP-1 RA that is an option for treatment of T2DM. Typical of all new glucose-lowering agents, its CV safety profile is of great interest. Areas covered: This article outlines the… read more here.

Keywords: treatment; safety; liraglutide; cardiovascular safety ... See more keywords
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Newer formulations of intravenous iron: a review of their chemistry and key safety aspects – hypersensitivity, hypophosphatemia, and cardiovascular safety

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Published in 2021 at "Expert Opinion on Drug Safety"

DOI: 10.1080/14740338.2021.1912010

Abstract: ABSTRACT Introduction: The newest intravenous (IV) iron products show an improved safety profile over predecessors, allowing for the rapid administration of relatively high doses. Ferric derisomaltose (FDI; also known as iron isomaltoside), ferric carboxymaltose (FCM),… read more here.

Keywords: safety; chemistry; fcm; cardiovascular safety ... See more keywords

Cardiovascular safety of COVID-19 studies: vaccines in real-world a systematic review and meta-analysis.

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Published in 2022 at "Expert review of vaccines"

DOI: 10.1080/14760584.2023.2150169

Abstract: OBJECTIVES To evaluate the cardiovascular safety of COVID-19 vaccines in the real world. METHODS Studies reported on any COVID-19 vaccine-related cardiovascular events in the population aged ≥ 12 years between January 1, 2020 and June… read more here.

Keywords: vaccines real; meta analysis; safety covid; risk ... See more keywords

Cardiovascular Safety of Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate in Virologically Suppressed PLWHIV: A Comparative Analysis of CVD Scores

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Published in 2024 at "AIDS Research and Human Retroviruses"

DOI: 10.1089/aid.2024.0066

Abstract: The Aim of this study is to assess the cardiovascular safety of doravirine/lamivudine/tenofovir disoproxil fumarate (DOR/3TC/TDF). We analyzed data from 37 virologically suppressed people living with HIV starting DOR/3TC/TDF, collecting viro-immunological and metabolic parameters as… read more here.

Keywords: doravirine lamivudine; safety doravirine; reduction; significant reduction ... See more keywords