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Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2016_15
Abstract: Histamine mediates a wide range of cellular responses, including allergic and inflammatory reactions, gastric acid secretion, and neurotransmission in the central nervous system. Histamine also exerts a series of actions upon the cardiovascular system but…
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Keywords:
system;
function;
system histamine;
regulation cardiovascular ... See more keywords
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Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-1671-9_20
Abstract: In recent years, progress in the field of high-throughput sequencing technology and its application to a wide variety of biological specimens has greatly advanced the discovery and cataloging of a diverse set of non-coding RNAs…
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Keywords:
biogenesis;
biogenesis function;
rnas biogenesis;
cardiovascular system ... See more keywords
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Published in 2020 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-020-02659-x
Abstract: Apoptosis is a highly conserved physiological process of programmed cell death which is critical for proper organism development, tissue maintenance, and overall organism homeostasis. Proper regulation of cell removal is crucial, as both excessive and…
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Keywords:
mechanical stimuli;
apoptosis;
cardiovascular system;
apoptosis cardiovascular ... See more keywords
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Published in 2019 at "Endocrine"
DOI: 10.1007/s12020-019-01925-w
Abstract: PurposeHeart disease is a major cause of mortality and disability worldwide. Melatonin is a neuroendocrine hormone and has been found to be protective in heart disease. However, the molecular basis underlying this cardioprotective effect is…
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Keywords:
sensitive genes;
analysis;
genes cardiovascular;
melatonin sensitive ... See more keywords
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Published in 2019 at "American Journal of Cardiovascular Drugs"
DOI: 10.1007/s40256-019-00345-5
Abstract: Adenosine is an endogenous nucleoside with a short half-life that regulates many physiological functions involving the heart and cardiovascular system. Among the cardioprotective properties of adenosine are its ability to improve cholesterol homeostasis, impact platelet…
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Keywords:
a2a receptor;
cholesterol;
platelet;
receptor ... See more keywords
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Published in 2017 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2017.06.017
Abstract: Cardiac obesity makes an important contribution to the pathogenesis of cardiovascular disease. One of the important pathways of this contribution is the inflammatory process that takes place in the adipose tissue. In this review, we…
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Keywords:
system associated;
cardiovascular system;
adipose tissue;
pathology ... See more keywords
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Published in 2020 at "Pharmacological research"
DOI: 10.1016/j.phrs.2019.104625
Abstract: Substantial experimental evidences support the hypothesis that dietary flavonoid intake has a favourable impact on cardiovascular diseases such as systemic, arterial hypertension and coronary artery diseases, which represent the leading cause of morbidity and mortality…
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Keywords:
system focus;
effects flavonoids;
flavonoids cardiovascular;
beneficial health ... See more keywords
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Published in 2019 at "Sleep medicine reviews"
DOI: 10.1016/j.smrv.2018.11.002
Abstract: Down syndrome (DS), the most common human chromosomal malformation, has an estimated annual incidence of one in 1000 live births worldwide. Sleep problems are common in children with DS, reported by parents in up to…
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Keywords:
sleep disordered;
sleep sleep;
sleep;
disordered breathing ... See more keywords
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Published in 2019 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2018.08.009
Abstract: Aging is the most critical risk factor for the development of cardiovascular diseases and their complications. Therefore, the fine-tuning of cellular response to getting older is an essential target for prospective therapies in cardiovascular medicine.…
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Keywords:
focus cardiovascular;
aging focus;
pharmacology;
nrf2 aging ... See more keywords
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Published in 2022 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-022-00678-w
Abstract: Cardiovascular diseases (CVDs) make a substantial contribution to the global burden of disease. Prevention strategies have succeeded in reducing the effect of acute CVD events and deaths, but the long-term consequences of cardiovascular risk factors…
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Keywords:
system;
immune organs;
autonomic nervous;
cardiovascular system ... See more keywords
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Published in 2020 at "Clinical science"
DOI: 10.1042/cs20200479
Abstract: The apelinergic system is widely expressed and acts through autocrine and paracrine signaling to exert protective effects, including vasodilatory, metabolic, and inotropic effects on the cardiovascular (CV) system. The apelin pathway's dominant physiological role has…
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Keywords:
system;
therapeutic implications;
apelin peptides;
interaction ... See more keywords