Cardiovascular Toxicities of Immune Checkpoint Inhibitors: JACC Review Topic of the Week.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2019.07.079
Abstract: Immune checkpoint inhibitors (ICIs) have been an important therapeutic advance in the field of cancer medicine, resulting in a significant improvement in survival of patients with advanced malignancies. Recent reports provided greater insights into the… read more here.
Keywords: immune checkpoint; checkpoint inhibitors; cardiovascular toxicities; review ... See more keywords
Cardiovascular toxicities of systemic treatments of prostate cancer: is oestrogen to the rescue?
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Urology"
DOI: 10.1038/nrurol.2017.127
Abstract: Cardiovascular toxicities of systemic treatments of prostate cancer: is oestrogen to the rescue? read more here.
Keywords: toxicities systemic; cardiovascular toxicities; prostate cancer; systemic treatments ... See more keywords
Mechanisms and clinical manifestations of cardiovascular toxicities associated with immune checkpoint inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical science"
DOI: 10.1042/cs20200331
Abstract: Immunotherapies have greatly expanded the armamentarium of cancer-directed therapies in the past decade, allowing the immune system to recognize and fight cancer. Immune checkpoint inhibitors (ICIs), in particular, have revolutionized cancer treatment and have demonstrated… read more here.
Keywords: immune checkpoint; toxicities associated; cancer; cardiovascular toxicities ... See more keywords
Risks of cardiovascular toxicities associated with ALK tyrosine kinase inhibitors in patients with non-small-cell lung cancer: a meta-analysis of randomized control trials.
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on drug safety"
DOI: 10.1080/14740338.2023.2182284
Abstract: BACKGROUND Anaplastic lymphoma kinases (ALK) tyrosine kinase inhibitors (TKIs) are targeted therapies used in advanced ALK-positive non-small cell lung cancers (NSCLC) which showed excellent efficacy and safety. However, ALK TKIs-associated cardiovascular toxicities [cardiac disorders, venous… read more here.
Keywords: meta analysis; toxicities associated; cardiovascular toxicities; alk tkis ... See more keywords
Cardiovascular toxicities associated with immune checkpoint inhibitors: An updated comprehensive disproportionality analysis of the FDA adverse event reporting system
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13707
Abstract: Immune checkpoint inhibitors (ICIs) have significantly improved clinical outcomes for a wide range of cancers but can also lead to cardiovascular toxicities. This study was to scientifically and systematically explore the association between cardiovascular toxicities… read more here.
Keywords: checkpoint inhibitors; immune checkpoint; associated immune; toxicities associated ... See more keywords
Does the HFA/ICOS tool overestimate the risk of cardiovascular toxicities in oncologic patients scheduled to receive anti-VEGF agents?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cardiovascular Medicine"
DOI: 10.2459/jcm.0000000000001346
Abstract: Letter to the Editor TheHeart Failure Association of the European Society of Cardiology (HFA) and the International Cardio-Oncology Society (ICOS) recently proposed the use of a chartbased tool for the baseline cardiovascular risk assessment of… read more here.
Keywords: patients scheduled; vegf agents; oncologic patients; anti vegf ... See more keywords
Cardiovascular Toxicities of Ibrutinib: A Pharmacovigilance Study Based on the United States Food and Drug Administration Adverse Event Reporting System Database
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DOI: 10.3390/ph16010098
Abstract: Background: Although ibrutinib has been widely used to treat haematological malignancies, many studies have reported associated cardiovascular events. These studies were primarily animal experiments and clinical trials. For more rational clinical drug use, a study… read more here.
Keywords: system; toxicities ibrutinib; reporting; cardiovascular toxicities ... See more keywords
Clinical Features and Outcomes of Immune Checkpoint Inhibitor-Associated Cardiovascular Toxicities.
Sign Up to like & getrecommendations! Published in 2022 at "Acta Cardiologica Sinica"
DOI: 10.6515/acs.202201_38(1).20210830b
Abstract: Background Despite the increasing prevalence of therapies utilizing immune checkpoint inhibitors (ICIs), the associated cardiovascular complications have been poorly reported. Given the fatality of ICI-related complications, especially myocarditis, optimal risk stratification to predict major adverse… read more here.
Keywords: immune checkpoint; ici related; cardiovascular toxicities; associated cardiovascular ... See more keywords