Mechanisms of cardiovascular toxicity induced by PM2.5: a review
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-16735-9
Abstract: An increasing number of studies have shown that exposure to particulate matter with a diameter ≤ 2.5 μm (PM2.5) could affect the onset and development of cardiovascular diseases. To explore the underlying mechanisms, the studies… read more here.
Keywords: induced pm2; toxicity induced; cardiovascular toxicity; toxicity ... See more keywords
In vivo cardiovascular toxicity induced by acetochlor in zebrafish larvae.
Sign Up to like & getrecommendations! Published in 2017 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.04.090
Abstract: The risk of acetochlor to human health is still unclear, prompting concern over its risk, especially to pesticide suicides population, occupational population (farmers, retailers and pharmaceutical workers), and special population (young children and infants, pregnant… read more here.
Keywords: zebrafish larvae; toxicity induced; cardiovascular toxicity; induced acetochlor ... See more keywords
Cardiovascular toxicity assessment of polyethylene nanoplastics on developing zebrafish embryos.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.131124
Abstract: Environmental exposure to nanoplastics is inevitable as the application of nanoplastics in our daily life is more and more extensively. So, the adverse effects of nanoplastics on human health are also gaining greater concerns. However,… read more here.
Keywords: embryos; cardiovascular toxicity; toxicity assessment; zebrafish embryos ... See more keywords
Molecular mechanisms of anthracycline cardiovascular toxicity.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical science"
DOI: 10.1042/cs20200301
Abstract: Anthracyclines are effective chemotherapeutic agents, commonly used in the treatment of a variety of hematologic malignancies and solid tumors. However, their use is associated with a significant risk of cardiovascular toxicities and may result in… read more here.
Keywords: mechanisms anthracycline; molecular mechanisms; anthracycline cardiovascular; toxicity ... See more keywords
Cardiovascular toxicity of PI3Kα inhibitors.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical science"
DOI: 10.1042/cs20200302
Abstract: The phosphoinositide 3-kinases (PI3Ks) are a family of intracellular lipid kinases that phosphorylate the 3'-hydroxyl group of inositol membrane lipids, resulting in the production of phosphatidylinositol 3,4,5-trisphosphate from phosphatidylinositol 4,5-bisphosphate. This results in downstream effects,… read more here.
Keywords: pi3k inhibitors; role; inhibition; cardiovascular toxicity ... See more keywords
Out of the frying pan and into the fire: damage-associated molecular patterns and cardiovascular toxicity following cancer therapy
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutic Advances in Cardiovascular Disease"
DOI: 10.1177/1753944717729141
Abstract: Cardio-oncology is a new and rapidly expanding field that merges cancer and cardiovascular disease. Cardiovascular disease is an omnipresent side effect of cancer therapy; in fact, it is the second leading cause of death in… read more here.
Keywords: cancer; cancer therapy; disease; cardiovascular toxicity ... See more keywords
Cardio-Oncology: mechanisms of cardiovascular toxicity
Sign Up to like & getrecommendations! Published in 2018 at "F1000Research"
DOI: 10.12688/f1000research.12598.1
Abstract: The therapeutic options available to treat a wide range of malignancies are rapidly increasing. At the same time, the population being treated is aging with more cardiovascular risk factors, comorbid conditions, and associated poor cardiac… read more here.
Keywords: cardiovascular toxicity; mechanisms cardiovascular; oncology mechanisms; cardio oncology ... See more keywords
Epigenetic Mechanisms Involved in the Cardiovascular Toxicity of Anticancer Drugs
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.658900
Abstract: The cardiovascular toxicity of anticancer drugs promotes the development of cardiovascular diseases. Therefore, cardiovascular toxicity is an important safety issue that must be considered when developing medications and therapeutic applications to treat cancer. Among anticancer… read more here.
Keywords: epigenetic mechanisms; anticancer drugs; toxicity anticancer; cardiovascular toxicity ... See more keywords
Cardiovascular toxicity of tyrosine kinase inhibitors during cancer treatment: Potential involvement of TRPM7
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1002438
Abstract: Receptor tyrosine kinases (RTKs) are a class of membrane spanning cell-surface receptors that transmit extracellular signals through the membrane to trigger diverse intracellular signaling through tyrosine kinases (TKs), and play important role in cancer development.… read more here.
Keywords: tyrosine; cardiovascular toxicity; trpm7; cancer treatment ... See more keywords
Abacavir Increases Purinergic P2X7 Receptor Activation by ATP: Does a Pro-inflammatory Synergism Underlie Its Cardiovascular Toxicity?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.613449
Abstract: The cardiovascular toxicity of Abacavir is related to its purinergic structure. Purinergic P2X7-receptors (P2X7R), characterized by activation by high concentrations of ATP and with high plasticity, seem implicated. We appraise the nature of the interplay… read more here.
Keywords: purinergic p2x7; atp; cardiovascular toxicity; cbv ... See more keywords
Cardiovascular Toxicity Induced by Vascular Endothelial Growth Factor Inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13020366
Abstract: Cardiotoxicity is an important side effect of vascular endothelial growth factor (VEGF) inhibitors therapy used in the treatment of various malignancies, leading to increased morbidity and mortality. Arterial hypertension, cardiac ischemia with the acceleration of… read more here.
Keywords: cardiovascular toxicity; endothelial growth; vegf inhibitors; growth factor ... See more keywords