Changes in murine respiratory dynamics induced by aerosolized carfentanil inhalation: efficacy of naloxone and naltrexone.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.09.012
Abstract: Carfentanil (CRF) is an extremely potent opioid capable of inducing fatal respiratory depression. Naloxone (NX) and naltrexone (NTX) are opioid antagonists for which the efficacy against CRF remains largely unexplored. In this study, the effects… read more here.
Keywords: naloxone naltrexone; changes murine; respiratory; carfentanil ... See more keywords
Strategic Decision-Making by a Forensic Toxicology Laboratory in Response to an Emerging NPS: Detection, Quantitation, and Interpretation of Carfentanil in Death Investigations in Ontario, Canada, July 2017 to June 2018.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkab079
Abstract: The proliferation of novel psychoactive substances (NPS) and the current opioid epidemic creates challenges for a toxicology laboratory. Methods capable of detecting and quantitating emerging compounds must be established despite limited information on toxicologically relevant… read more here.
Keywords: death investigations; carfentanil; toxicology; toxicology laboratory ... See more keywords
Carfentanil Blood Concentrations in Impaired Driving Investigations in Ontario, Canada
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Analytical Toxicology"
DOI: 10.1093/jat/bkac039
Abstract: Abstract Carfentanil is a potent opioid with no medical use in humans; it presents a serious threat to public health and road safety due to its presence in the illicit drug supply, the potency of… read more here.
Keywords: impaired driving; carfentanil blood; blood concentrations; carfentanil ... See more keywords
Assessment of abuse potential of carfentanil
Sign Up to like & getrecommendations! Published in 2023 at "Addiction Biology"
DOI: 10.1111/adb.13265
Abstract: Carfentanil, as a fentanyl analogue, is a potent synthetic opioid. It has been controlled in many countries, and its emergence has been highlighted by many recent reports. However, although discriminative stimulus effects of carfentanil in… read more here.
Keywords: fentanyl heroin; potential carfentanil; abuse potential; carfentanil fentanyl ... See more keywords