LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "cargo" as a keyword



Spatial regulation of ARL3 and GSF-mediated lipidated cargo trafficking in the primary cilium.

Sign Up to like & get
recommendations! Published in 2025 at "FEBS letters"

DOI: 10.1002/1873-3468.70145

Abstract: Lipid‐modified proteins are essential for ciliary signaling and structure, but their hydrophobic modifications hinder cytosolic transport and selective delivery. GDI‐like solubilizing factors (GSFs), such as PDE6D and UNC119A/B, bind lipid moieties to shield cargo proteins… read more here.

Keywords: arl3; cargo; spatial regulation; primary cilium ... See more keywords
Photo by nci from unsplash

Extracellular vesicles and oncogenic signaling

Sign Up to like & get
recommendations! Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12855

Abstract: In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic markers for cancer therapy. While the field of EV research is rapidly developing and their application as vehicles for therapeutic cargo is being… read more here.

Keywords: extracellular vesicles; oncogenic signaling; signaling cascades; vesicles oncogenic ... See more keywords

Red/Far-Red Light Switchable Cargo Attachment and Release in Bacteria-Driven Microswimmers.

Sign Up to like & get
recommendations! Published in 2019 at "Advanced healthcare materials"

DOI: 10.1002/adhm.201900956

Abstract: In bacteria-driven microswimmers, i.e., bacteriabots, artificial cargos are attached to flagellated chemotactic bacteria for active delivery with potential applications in biomedical technology. Controlling when and where bacteria bind and release their cargo is a critical… read more here.

Keywords: red far; red light; far red; bacteria driven ... See more keywords

Multifunctional 3D‐Printed Pollen Grain‐Inspired Hydrogel Microrobots for On‐Demand Anchoring and Cargo Delivery

Sign Up to like & get
recommendations! Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202209812

Abstract: While a majority of wireless microrobots have shown multi‐responsiveness to implement complex biomedical functions, their functional executions are strongly dependent on the range of stimulus inputs, which curtails their functional diversity. Furthermore, their responsive functions… read more here.

Keywords: cargo; grain inspired; multifunctional printed; pollen ... See more keywords

Bro1 family proteins harmonize cargo sorting with vesicle formation

Sign Up to like & get
recommendations! Published in 2022 at "BioEssays"

DOI: 10.1002/bies.202100276

Abstract: The Endosomal Sorting Complexes Required for Transport (ESCRTs) drive membrane remodeling in a variety of cellular processes that include the formation of endosomal intralumenal vesicles (ILVs) during multivesicular body (MVB) biogenesis. During MVB sorting, ESCRTs… read more here.

Keywords: cargo; proteins harmonize; harmonize cargo; formation ... See more keywords

Efficient Synthesis of Cleavable Cell‐Penetrating Peptide–Cargo Conjugate via Low‐Equivalent of Cell‐Penetrating Peptide Activated by 2,2′‐Dithiodipyridine

Sign Up to like & get
recommendations! Published in 2025 at "ChemBioChem"

DOI: 10.1002/cbic.202500032

Abstract: Cell‐penetrating peptides (CPPs) are favored for protein delivery due to their efficiency, rapidity, and low toxicity. However, conjugation of CPPs to proteins often requires significant amounts of CPPs to ensure yields, which also may result… read more here.

Keywords: cargo; synthesis cleavable; penetrating peptide; cell ... See more keywords

Stimulus‐dependent modifications in astrocyte‐derived extracellular vesicle cargo regulate neuronal excitability

Sign Up to like & get
recommendations! Published in 2019 at "Glia"

DOI: 10.1002/glia.23708

Abstract: Extracellular vesicles have now emerged as key players in cell‐to‐cell communication. This is particularly important in the central nervous system, where glia–neuron cross‐talk helps maintain normal neuronal function. Astrocyte‐derived extracellular vesicles (ADEVs) secreted constitutively promote… read more here.

Keywords: response; stimulus; adevs secreted; derived extracellular ... See more keywords

Mitochondrial cargo export in exosomes: Possible pathways and implication in disease biology

Sign Up to like & get
recommendations! Published in 2023 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30967

Abstract: Exosome biogenesis occurs parallel to multiple endocytic traffic routes. These coexisting routes drive cargo loading in exosomes via overlapping of exosome biogenesis with endosomal pathways. One such pathway is autophagy which captures damaged intracellular organelles… read more here.

Keywords: cargo; cargo export; export exosomes; exosome biogenesis ... See more keywords

Hypoxia and extracellular vesicles: A review on methods, vesicular cargo and functions

Sign Up to like & get
recommendations! Published in 2020 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.12002

Abstract: Abstract Hypoxia is an essential hallmark of several serious diseases such as cardiovascular and metabolic disorders and cancer. A decline in the tissue oxygen level induces hypoxic responses in cells which strive to adapt to… read more here.

Keywords: extracellular vesicles; vesicles review; review methods; hypoxia extracellular ... See more keywords

TurboID‐Mediated Profiling of Glioblastoma‐Derived Extracellular Vesicle Cargo Proteins

Sign Up to like & get
recommendations! Published in 2025 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.70158

Abstract: ABSTRACT Glioblastoma (GBM), the most aggressive primary brain tumour in adults, presents significant challenges due to its universal recurrence and limited survival rates. A key driver of GBM progression is the subpopulation of brain tumour‐initiating… read more here.

Keywords: cargo; turboid mediated; profiling glioblastoma; glioblastoma ... See more keywords

Crosslinked and Multi-Responsive Polymeric Vesicles as A Platform to Study Enzyme-mediated Undocking Behavior: Towards Future Artificial Organelle Communication.

Sign Up to like & get
recommendations! Published in 2023 at "Macromolecular rapid communications"

DOI: 10.1002/marc.202200885

Abstract: Various cellular functions are successfully mimicked, opening the door to the next generation of therapeutic approaches and systems biology. Here, the first steps are taken towards the construction of artificial organelles for mimicking cell communication… read more here.

Keywords: cargo; communication; multi responsive; polymeric vesicles ... See more keywords