Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution
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DOI: 10.1038/s41598-021-03729-3
Abstract: Shuttling of macromolecules between nucleus and cytoplasm is a tightly regulated process mediated through specific interactions between cargo and nuclear transport proteins. In the classical nuclear import pathway, importin alpha recognizes cargo exhibiting a nuclear… read more here.
Keywords: importin alpha; importin; alpha isoforms; cargo free ... See more keywords
Multifunctional Cargo-Free Nanomedicine for Cancer Therapy
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DOI: 10.3390/ijms19102963
Abstract: Nanocarriers encapsulating multiple chemotherapeutics are a promising strategy to achieve combinational chemotherapy for cancer therapy; however, they generally use exotic new carriers without therapeutic effect, which usually suffer from carrier-related toxicity issues, as well as… read more here.
Keywords: cancer therapy; cargo free; cancer; free nanomedicine ... See more keywords