Ribavirin inhibits the growth and ascites formation of hepatocellular carcinoma through downregulation of type I CARM1 and type II PRMT5.
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DOI: 10.1016/j.taap.2021.115829
Abstract: Type I co-activator-associated arginine methyltransferase (CARM1) and type II protein arginine methyltransferase 5 (PRMT5) are highly expressed in multiple cancers including liver cancer and their overexpression contributes to poor prognosis, thus making them promising therapeutic… read more here.
Keywords: carm1 type; hcc; prmt5; growth ... See more keywords