Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b01723
Abstract: Human acid ceramidase (AC) is a lysosomal cysteine amidase, which has received a great deal of interest in recent years as a potential target for the development of new therapeutics against melanoma and glioblastoma tumors.… read more here.
Keywords: inhibition; carmofur; molecular mechanism; ceramidase ... See more keywords
A new insight into the transfer and delivery of anti-SARS-CoV-2 drug Carmofur with the assistance of graphene oxide quantum dot as a highly efficient nanovector toward COVID-19 by molecular dynamics simulation
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra01420c
Abstract: Currently, a preventive and curative treatment for COVID-19 is an urgent global issue. According to the fact that nanomaterial-based drug delivery systems as risk-free approaches for successful therapeutic strategies may led to immunization against COVID-19… read more here.
Keywords: oxide quantum; carmofur; graphene oxide; drug ... See more keywords
Molecular mechanism of inhibition of acid ceramidase by carmofur.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medicinal Chemistry"
DOI: 10.2210/pdb6mhm/pdb
Abstract: Human acid ceramidase (AC) is a lysosomal cysteine amidase, which has received a great deal of interest in recent years as a potential target for the development of new therapeutics against melanoma and glioblastoma tumors.… read more here.
Keywords: acid ceramidase; carmofur; ceramidase; inhibition ... See more keywords