Systematic investigations of novel validity parameters in urine drug testing and prevalence of urine adulteration in a two-year cohort.
Sign Up to like & getrecommendations! Published in 2018 at "Drug testing and analysis"
DOI: 10.1002/dta.2447
Abstract: Urinalysis is well established for drug screening. Various methods of urine adulteration such as dilution, addition of oxidative/reductive chemicals or detergents, and handing over urine-like fluids are used to circumvent a positive screen. Validity parameters… read more here.
Keywords: fake urine; urine adulteration; drug; adulteration ... See more keywords
Differential structural features in soleus and gastrocnemius of carnitine‐treated cancer cachectic rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28992
Abstract: Muscle wasting is associated with chronic diseases and cancer. Elucidation of the biological mechanism involved in the process of muscle mass loss and cachexia may help identify therapeutic targets. We hypothesized that l‐carnitine treatment may… read more here.
Keywords: muscle; soleus gastrocnemius; structural features; differential structural ... See more keywords
The decision to discontinue screening for carnitine uptake disorder in New Zealand
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12030
Abstract: When screening for carnitine uptake disorder (CUD), the New Zealand (NZ) newborn screening (NBS) service identified infants as screen‐positive if they had initial and repeat free carnitine (C0) levels of less than 5.0 μmol/L. Since… read more here.
Keywords: uptake disorder; new zealand; carnitine uptake; screening carnitine ... See more keywords
Plasma carnitine concentrations in Medium‐chain acyl‐CoA dehydrogenase deficiency: lessons from an observational cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12537
Abstract: Our aim was to study the effect of secondary carnitine deficiency (SCD) and carnitine supplementation on important outcome measures for persons with medium‐chain Acyl–CoA dehydrogenase deficiency (MCADD). We performed a large retrospective observational study using… read more here.
Keywords: carnitine supplementation; carnitine; persons mcadd; deficiency ... See more keywords
Dietary l‐carnitine prevents histopathological changes in tilapia (Oreochromis Niloticus) exposed to cylindrospermopsin
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22229
Abstract: Cylindrospermopsin (CYN) is a cytotoxin highly water‐soluble, which is easily taken up by several aquatic organisms. CYN acts as a potent protein and glutathione synthesis inhibitor, as well as inducing genotoxicity, oxidative stress, and histopathological… read more here.
Keywords: cylindrospermopsin; tilapia oreochromis; cyn; oreochromis niloticus ... See more keywords
Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer's disease in vitro model.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of toxicology"
DOI: 10.1007/s00204-021-03104-1
Abstract: Mitochondrial deregulation has emerged as one of the earliest pathological events in Alzheimer's disease (AD), the most common age-related neurodegenerative disorder. Improvement of mitochondrial function in AD has been considered a relevant therapeutic approach. L-carnitine… read more here.
Keywords: mechanistic perspectives; alzheimer disease; mitochondrial function; perspectives differential ... See more keywords
Impact of l-carnitine on imatinib-related muscle cramps in patients with gastrointestinal stromal tumor
Sign Up to like & getrecommendations! Published in 2019 at "Investigational New Drugs"
DOI: 10.1007/s10637-019-00860-x
Abstract: Introduction Muscle cramps constitute one of the leading adverse events of imatinib, the standard first-line treatment for advanced gastrointestinal stromal tumor (GIST). This study aims to assess the impact of l-carnitine on relieving cramps in… read more here.
Keywords: cramps patients; gastrointestinal stromal; muscle cramps; carnitine ... See more keywords
Anti-kindling effect of Ginkgo biloba leaf extract and L-carnitine in the pentylenetetrazol model of epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-022-19251-6
Abstract: Epilepsy is one of the most common serious brain disorders, affecting about 1% of the population all over the world. Ginkgo biloba extract (GbE) and L-carnitine (LC) reportedly possess the antioxidative activity and neuroprotective potential.… read more here.
Keywords: ptz; epilepsy; ginkgo biloba; carnitine ... See more keywords
Carnitine Responsive Migraine Headache Syndrome: Case Report and Review of the Literature
Sign Up to like & getrecommendations! Published in 2021 at "Current Pain and Headache Reports"
DOI: 10.1007/s11916-021-00936-5
Abstract: Purpose of Review To review carnitine’s role in migraine and headache, present a case of a patient with intractable chronic migraine refractory to medications but exquisitely responsive to mitochondrial cofactors with a particularly prompt response… read more here.
Keywords: migraine; case; migraine headache; review ... See more keywords
Effect of l-carnitine on cardiotoxicity and apoptosis induced by imatinib through PDGF/ PPARγ /MAPK pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108866
Abstract: A tyrosine kinase inhibitor Imatinib (IM) is used in the treatment of different varieties of cancers. The current study was designed to explore the beneficial role of l-carnitine against IM-induced cardiotoxicity in rats. Male albino… read more here.
Keywords: ppar; mapk pathways; ppar mapk; pdgf ppar ... See more keywords
Effect of dietary l-carnitine and lipid levels on growth performance, blood biochemical parameters and antioxidant status in juvenile common carp (Cyprinus carpio)
Sign Up to like & getrecommendations! Published in 2017 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2017.08.013
Abstract: Abstract An 8-week feeding trial was carried out under controlled condition to evaluate the effect of dietary l -carnitine and lipid levels on growth performance, whole body composition, blood biochemical parameters and antioxidant status of… read more here.
Keywords: dietary carnitine; growth performance; common carp; carnitine ... See more keywords