Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition☆
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Drug Delivery Reviews"
DOI: 10.1016/j.addr.2016.06.004
Abstract: &NA; Drug pharmacokinetics is influenced by the function of metabolising enzymes and influx/efflux transporters. Genetic variability of these genes is known to impact on clinical therapies. Solute Carrier Transporters (SLCs) are the primary influx transporters… read more here.
Keywords: recent advance; carrier transporters; solute carrier; drug ... See more keywords
The Role of the SLC Transporters Protein in the Neurodegenerative Disorders
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Psychopharmacology and Neuroscience"
DOI: 10.9758/cpn.2020.18.2.174
Abstract: The solute carrier (SLC) superfamily is one of the major sub-groups of membrane proteins in mammalian cells. The solute carrier proteins include more than 400 different membrane-spanning solute carriers organized with 65 families in the… read more here.
Keywords: role; carrier transporters; solute carrier; neurodegenerative disorders ... See more keywords