Cre/LoxP Genetic Recombination Sustains Cartilage Anabolic Factor Expression in Hyaluronan Encapsulated MSCs Alleviates Intervertebral Disc Degeneration
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DOI: 10.3390/biomedicines10030555
Abstract: (1) Background: Inexplicable low back and neck pain frequently results from spinal disc degeneration with an imbalanced intervertebral disc (IVD) cell homeostasis. We hypothesize that introducing MSC expressing a sustained cartilage-anabolic factor in the IVD… read more here.
Keywords: anabolic factor; disc degeneration; cre loxp; cartilage anabolic ... See more keywords