Mechanical Induction of Osteoarthritis Traits in a Cartilage-on-a-Chip Model.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1693-2_14
Abstract: The present lack of effective therapies for osteoarthritis, the most diffused musculoskeletal disease, correlates with the absence of representative in vitro disease models. Microfabrication techniques and soft lithography allow the development of organs and tissues… read more here.
Keywords: cartilage chip; osteoarthritis; chip model; mechanical induction ... See more keywords
Cartilage-on-a-chip to aid OA drug development
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-019-0270-2
Abstract: Nature reviews | Rheumatology The development of disease-modifying osteoarthritis (OA) drugs (DMOADs) has been hampered by a lack of experimental models that accurately recapitulate the disease phenotype. However, a new cartilage-on-a-chip device looks set to… read more here.
Keywords: cartilage chip; rheumatology; device; development ... See more keywords