Long‐Term Recruitment of Endogenous M2 Macrophages by Platelet Lysate‐Rich Plasma Macroporous Hydrogel Scaffold for Articular Cartilage Defect Repair
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202101661
Abstract: After cartilage damage, a large number of monocytes/macrophages infiltrate into adjacent synovium and the resident macrophages in synovial tissue transform to activated macrophages (M1), which secrete pro‐inflammatory cytokines to induce sustained inflammation and chondrocyte apoptotic.… read more here.
Keywords: cartilage defect; repair; long term; plpmh scaffold ... See more keywords
Influence of cartilage defects and a collagen gel on integrity of corresponding intact cartilage: a biomechanical in-vitro study
Sign Up to like & getrecommendations! Published in 2024 at "Archives of Orthopaedic and Trauma Surgery"
DOI: 10.1007/s00402-024-05530-z
Abstract: Numerous cartilage repair procedures have been developed for focal lesions to minimize suffering and possibly prevent the development of osteoarthritis with a focus on so-called one-step procedures. The aim of this work was to investigate… read more here.
Keywords: hour; chondrofiller; cartilage defect; damage ... See more keywords
Autologous mesenchymal stem cell application for cartilage defect in recurrent patellar dislocation: A case report
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Surgery Case Reports"
DOI: 10.1016/j.ijscr.2019.01.031
Abstract: Highlights • This is a novel management of a 21-year-old male with recurrent patellar dislocation.• Fulkerson procedure was to realign the patella.• Mesenchymal stem cell application was used for the articular cartilage defect.• The outcome… read more here.
Keywords: cell application; patellar dislocation; cartilage defect; recurrent patellar ... See more keywords
Stearic acid methyl ester promotes migration of mesenchymal stem cells and accelerates cartilage defect repair
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Orthopaedic Translation"
DOI: 10.1016/j.jot.2019.09.008
Abstract: Background Mesenchymal stem cells (MSCs) can be easily expanded without losing the ability of multilineage differentiation, including oesteogenic, chondrogenic and adipogenic differentiation. These characters make MSCs a promising cell resource for cartilage defect repair. MSCs… read more here.
Keywords: cartilage defect; effect; migration; mscs ... See more keywords
Near-infrared light-controlled kartogenin delivery of multifunctional Prussian blue nanocomposites for cartilage defect repair.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d3nr00205e
Abstract: Articular cartilage injury repair remains a challenge for clinicians and researchers. Mesenchymal stem cells (MSCs) have multiple differentiation potentials and can be induced to differentiate into the chondrogenic lineage for cartilage defect repair; however, the… read more here.
Keywords: cartilage defect; repair; differentiation; prussian blue ... See more keywords
Exosomes derived from platelet-rich plasma present a novel potential in repairing knee articular cartilage defect combined with cyclic peptide-modified β-TCP scaffold
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-024-05202-z
Abstract: The aim of this study was to investigate the therapeutic effects and mechanisms of PRP-exos combined with cyclic peptide-modified β-TCP scaffold in the treatment of rabbit knee cartilage defect. PRP-exos were extracted and characterized by… read more here.
Keywords: cartilage defect; prp exos; cyclic peptide;
Effects of different microfracture drilling parameters on bone quality: a finite element analysis
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2024.1515136
Abstract: Background Microfracture drilling is a surgical technique that involves creating multiple perforations in areas of cartilage defects to recruit stem cells from the bone marrow, thereby promoting cartilage regeneration in the knee joint. Increasing the… read more here.
Keywords: microfracture drilling; drilling parameters; cartilage defect; microfracture ... See more keywords